{"id":"W2037378800","doi":"10.1155/2009/904568","title":"Viral Vector Induction of CREB Expression in the Periaqueductal Gray Induces a Predator Stress-Like Pattern of Changes in pCREB Expression, Neuroplasticity, and Anxiety in Rodents","year":2009,"lang":"en","type":"article","venue":"Neural Plasticity","topic":"Stress Responses and Cortisol","field":"Neuroscience","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"Memorial University of Newfoundland","funders":"Canadian Institutes of Health Research","keywords":"CREB; Periaqueductal gray; Amygdala; Anxiogenic; Internal medicine; Neuroscience; Endocrinology; Psychology; Biology; Central nervous system; Medicine; Anxiolytic; Transcription factor; Receptor; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007065145,0.0002451664,0.0003454318,0.0002792624,0.00006001209,0.00004379796,0.0003648726,0.0001299791,0.00001863246],"category_scores_gemma":[0.0006855731,0.0001783498,0.00004059165,0.000434395,0.0001579325,0.0003296063,0.0001468839,0.0004456819,5.336679e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002247597,"about_ca_system_score_gemma":0.00003020428,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000233562,"about_ca_topic_score_gemma":0.0005344697,"domain_scores_codex":[0.9976177,0.0005198527,0.0004806239,0.0005310386,0.0005017157,0.000349066],"domain_scores_gemma":[0.9990016,0.0004531523,0.00024354,0.0002068349,0.00002880459,0.00006603508],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0006322631,0.0003871055,0.07145787,0.0000443158,6.569162e-7,0.00002980818,0.001438117,0.0002594744,0.9223834,0.000005746715,0.00001406507,0.003347218],"study_design_scores_gemma":[0.0005677153,0.0003354096,0.5414433,0.0001729986,0.000003848505,0.00001393862,0.0002412551,0.001097026,0.456004,0.00001981094,0.000002455952,0.00009827341],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9990877,0.00004342271,0.00001901915,0.0001031233,0.0002288838,0.0003951048,0.00009223462,0.00001560309,0.00001489094],"genre_scores_gemma":[0.9996108,0.0001481504,0.00001377015,0.0001282226,0.00005527938,0.00002500338,0.000003021088,0.00001196751,0.000003727549],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4699854,"threshold_uncertainty_score":0.7272893,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02567370642319512,"score_gpt":0.2648829381108522,"score_spread":0.2392092316876571,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}