{"id":"W2037378800","doi":"10.1155/2009/904568","title":"Viral Vector Induction of CREB Expression in the Periaqueductal Gray Induces a Predator Stress-Like Pattern of Changes in pCREB Expression, Neuroplasticity, and Anxiety in Rodents","year":2009,"lang":"en","type":"article","venue":"Neural Plasticity","topic":"Stress Responses and Cortisol","field":"Neuroscience","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"Memorial University of Newfoundland","funders":"Canadian Institutes of Health Research","keywords":"CREB; Periaqueductal gray; Amygdala; Anxiogenic; Internal medicine; Neuroscience; Endocrinology; Psychology; Biology; Central nervous system; Medicine; Anxiolytic; Transcription factor; Receptor; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008104288,0.0003662395,0.0001739431,0.0002819714,0.0001054224,0.0002005845,0.0001529855,0.0002221036,0.001312751],"category_scores_gemma":[0.0001290494,0.0001703886,0.0002381731,0.00008465534,0.0004875724,0.0002201565,0.000223039,0.0007552753,0.0001656182],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002216466,"about_ca_system_score_gemma":0.0001857677,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006025101,"about_ca_topic_score_gemma":0.001090039,"domain_scores_codex":[0.9998534,0.00001181304,0.000008114648,0.0000402918,0.00003171065,0.00005467636],"domain_scores_gemma":[0.9998865,0.000009862295,0.0000398327,0.00001567294,0.00000900648,0.0000390279],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001438542,0.00004976414,0.0001573807,0.00001898769,0.000004578473,0.0000443273,0.00002017431,0.00002307194,0.9984817,0.00009077632,0.00001952509,0.0009458307],"study_design_scores_gemma":[0.00006665188,0.002116016,0.01412814,0.00001932387,0.00003411577,0.0003977249,0.00009787265,0.0009168896,0.980846,0.0002795905,0.001083842,0.00001385733],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.998051,0.0002864924,0.001032031,0.00006878756,0.00002378126,0.00001489165,0.00009845529,0.00005345657,0.0003709213],"genre_scores_gemma":[0.996447,0.0003432027,0.001288516,0.00005718359,0.00001244042,0.00004389887,0.0002250272,0.00002244629,0.001560271],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001312751,"threshold_uncertainty_score":0.004391611,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02567370642319512,"score_gpt":0.2648829381108522,"score_spread":0.2392092316876571,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}