{"id":"W2037393257","doi":"10.1158/1078-0432.mechres-b45","title":"Abstract B45: Met-Dependent Positive and Negative Signaling Cascades in Gastric Cancer Cells","year":2012,"lang":"en","type":"article","venue":"Clinical Cancer Research","topic":"Cancer Mechanisms and Therapy","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre","funders":"","keywords":"Signal transduction; Phosphorylation; Autocrine signalling; Cell signaling; Cancer research; Receptor tyrosine kinase; Hepatocyte growth factor; Biology; Cell biology; Cancer; C-Met; Cancer cell; Receptor; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.003417311,0.0001811675,0.0005283657,0.0002555661,0.000118914,0.0000410717,0.0001307378,0.0002080366,0.001693855],"category_scores_gemma":[0.0002229866,0.0001474119,0.0001146908,0.0005144853,0.0002805379,0.000168244,0.00011582,0.001445312,0.00003207372],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004724469,"about_ca_system_score_gemma":0.0005173991,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.008814372,"about_ca_topic_score_gemma":0.001036449,"domain_scores_codex":[0.9970592,0.0003121682,0.0005526309,0.000472895,0.0007387159,0.0008643944],"domain_scores_gemma":[0.997446,0.001363824,0.00009996311,0.0002331997,0.0002889177,0.0005680913],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.007582166,0.001808194,0.2319536,0.0004230461,0.0006763628,0.0003130117,0.004966475,0.00006923152,0.2594486,0.0008800136,0.002122894,0.4897564],"study_design_scores_gemma":[0.009940271,0.002085365,0.6976879,0.001412601,0.0001395938,0.00002775736,0.002919448,0.0001238011,0.2794804,0.001486712,0.004110014,0.0005861294],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9852681,0.01136868,0.00002805795,0.001222108,0.0004540096,0.0007641266,0.00006708445,0.00001936121,0.0008084649],"genre_scores_gemma":[0.9881678,0.008950518,0.0002613055,0.0005546611,0.001310735,0.0002258447,0.00000330168,0.00003929167,0.000486587],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4891703,"threshold_uncertainty_score":0.9992187,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2298023231732635,"score_gpt":0.5310729923425993,"score_spread":0.3012706691693358,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}