{"id":"W2037403354","doi":"10.1158/0008-5472.sabcs13-p4-15-04","title":"Abstract P4-15-04: Synthesis and characterization of EGFR antibody-mediated tumor targeted “gold nanobombs” for treatment of locally advanced breast cancer","year":2013,"lang":"en","type":"article","venue":"Cancer Research","topic":"Radiopharmaceutical Chemistry and Applications","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Health Sciences Centre; University Health Network; Sunnybrook Health Science Centre","funders":"","keywords":"Conjugate; PEGylation; Chemistry; Antibody; Cancer research; PEG ratio; Internalization; Breast cancer; Cancer; Medicine; Molecular biology; Cell; Immunology; Internal medicine; Biochemistry; Biology; Polyethylene glycol","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001409731,0.0002487169,0.0001878893,0.0002494346,0.0001048384,0.0001163701,0.0002272173,0.0003206294,0.0009036039],"category_scores_gemma":[0.0001938367,0.0001210952,0.0001933437,0.0001082375,0.000133736,0.0001198621,0.0001283114,0.0001935212,0.000361214],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002724184,"about_ca_system_score_gemma":0.0001609113,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007449448,"about_ca_topic_score_gemma":0.000810485,"domain_scores_codex":[0.9999201,0.00001019176,0.000005314595,0.00001839951,0.0000321675,0.00001376503],"domain_scores_gemma":[0.9999198,0.00000895597,0.00001759172,0.000007779301,0.00002356649,0.00002221227],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000424234,0.00002430256,0.00007386887,0.00006399979,0.000003709466,0.00003287456,0.00001236666,0.0001403968,0.9977374,0.00004927443,0.00008383404,0.001735453],"study_design_scores_gemma":[0.00001519224,0.0003345873,0.0009124835,0.00000539866,0.000009522357,0.00005563462,0.000007115421,0.00076016,0.9952075,0.00001388895,0.002675073,0.00000347375],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9858802,0.001873809,0.008779624,0.0001216639,0.00005767008,0.0002440493,0.0004272111,0.0001601014,0.002455634],"genre_scores_gemma":[0.9767685,0.00053579,0.01596529,0.00007520333,0.00001056966,0.0001744599,0.0006127773,0.00005464051,0.005802608],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009036039,"threshold_uncertainty_score":0.00302285,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04792026201860468,"score_gpt":0.4053418325238023,"score_spread":0.3574215705051977,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}