{"id":"W2037493363","doi":"10.1002/chir.20718","title":"CD‐sensitive Zn‐porphyrin tweezer host‐guest complexes, part 2: <i>Cis‐</i> and <i>trans‐</i>3‐hydroxy‐4‐aryl/alkyl‐β‐lactams. A case study","year":2009,"lang":"en","type":"article","venue":"Chirality","topic":"Synthesis of β-Lactam Compounds","field":"Chemistry","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of New Brunswick","funders":"","keywords":"Chemistry; Stereocenter; Chirality (physics); Porphyrin; OPLS; Alkyl; Atropisomer; Aryl; Reactivity (psychology); Supramolecular chemistry; Stereochemistry; Hydrogen bond; Absolute configuration; Molecular recognition; Molecule; Enantioselective synthesis; Organic chemistry; Catalysis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001031231,0.0002101216,0.0002913317,0.0001147823,0.000157449,0.0003704461,0.0003004791,0.0002848865,0.0009355061],"category_scores_gemma":[0.0002346872,0.0001281397,0.0001078731,0.0001021725,0.0002415244,0.0002207905,0.0001964299,0.0003034475,0.0001401018],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004474218,"about_ca_system_score_gemma":0.0001288732,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006490035,"about_ca_topic_score_gemma":0.0008344377,"domain_scores_codex":[0.999916,0.00001193915,0.00000361953,0.00002449656,0.00002852734,0.00001553652],"domain_scores_gemma":[0.9999404,0.00003056864,0.00001351073,0.000004636269,0.000005039577,0.000005926481],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001516183,0.00002899072,0.0002169358,0.0001475462,0.00001102838,0.0001543591,0.00004675664,0.00518017,0.9889401,0.0004984717,0.0001333101,0.00449068],"study_design_scores_gemma":[0.00002026759,0.00007377268,0.0002670256,0.000002406118,0.000006490197,0.00009096706,0.00001367003,0.01408397,0.9843872,0.00005457448,0.0009916872,0.000008001967],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9911057,0.0006512371,0.006142317,0.00006956481,0.00001909796,0.00003590135,0.00005873187,0.0001684237,0.001748906],"genre_scores_gemma":[0.9942244,0.0002581038,0.004391746,0.00001980164,0.00000248573,0.00001561665,0.00003628163,0.00001161379,0.001039894],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009355061,"threshold_uncertainty_score":0.003246307,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02583963139738191,"score_gpt":0.2664732605599022,"score_spread":0.2406336291625203,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}