{"id":"W2037573370","doi":"10.1038/nmeth.1325","title":"Isolation of human iPS cells using EOS lentiviral vectors to select for pluripotency","year":2009,"lang":"en","type":"article","venue":"Nature Methods","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":306,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia; BC Cancer Agency; McMaster University; University of Toronto","funders":"","keywords":"Computational biology; Induced pluripotent stem cell; Isolation (microbiology); Biology; Viral vector; Cell biology; Computer science; Virology; Genetics; Embryonic stem cell; Bioinformatics; Recombinant DNA; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009038963,0.000158675,0.0002147253,0.0001368819,0.00009884402,0.00001666757,0.0002395838,0.0004124691,0.000008407786],"category_scores_gemma":[0.0002321692,0.0001527251,0.0001543228,0.0002503239,0.00002537457,0.000005688468,0.00005813658,0.0002456119,0.000001157513],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003286897,"about_ca_system_score_gemma":0.0000639017,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007280243,"about_ca_topic_score_gemma":0.000004954368,"domain_scores_codex":[0.9985886,0.0002749242,0.0002410213,0.000383828,0.0001893875,0.0003222516],"domain_scores_gemma":[0.999247,0.00004104912,0.00009602609,0.000314956,0.0002188207,0.00008214534],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009704397,0.00005017977,0.0001212798,0.00002958271,0.00002708915,5.505413e-7,0.00003938624,0.0001207549,0.9918123,0.00006366707,0.0007014753,0.006936631],"study_design_scores_gemma":[0.0003357318,0.0006892017,0.001151879,0.0000166918,0.00002364054,0.000002448013,0.00001064205,0.0006208462,0.992013,0.0003225477,0.00464918,0.0001642431],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6910487,0.000807438,0.3065073,0.00009970602,0.0002552858,0.0006145601,0.00002182719,0.00001316466,0.0006320433],"genre_scores_gemma":[0.7045543,0.000007696138,0.2945924,0.000124702,0.000203303,0.000006690223,0.00004134534,0.00001769687,0.0004519183],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01350558,"threshold_uncertainty_score":0.6227947,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02815300107516104,"score_gpt":0.4099887720261411,"score_spread":0.38183577095098,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}