{"id":"W2037708995","doi":"10.1016/j.tins.2009.10.002","title":"Post-transcriptional control of neurofilaments: New roles in development, regeneration and neurodegenerative disease","year":2009,"lang":"en","type":"review","venue":"Trends in Neurosciences","topic":"Skin and Cellular Biology Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":92,"is_retracted":false,"has_abstract":false,"ca_institutions":"Western University","funders":"Canadian Institutes of Health Research","keywords":"Axon; Biology; Neurofilament; Neuroscience; Amyotrophic lateral sclerosis; Cell biology; Transcriptional regulation; Transcription factor; Translation (biology); Regeneration (biology); Regulation of gene expression; Gene expression; Messenger RNA; Gene; Genetics; Disease; Immunology; Medicine; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002363903,0.0002590133,0.0004761758,0.0004141018,0.00005233454,0.00003092153,0.0003099621,0.0001467572,0.000009374676],"category_scores_gemma":[0.0001101074,0.0002124403,0.00009932646,0.0003914062,0.0002120884,0.000009604431,0.00005883505,0.0001798619,7.503996e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001168061,"about_ca_system_score_gemma":0.0004422166,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000866639,"about_ca_topic_score_gemma":0.0001175694,"domain_scores_codex":[0.9980143,0.0003745127,0.0004615575,0.0006770716,0.0002023486,0.0002701578],"domain_scores_gemma":[0.9994877,0.00002586272,0.0001420932,0.0001940551,0.00002930679,0.0001210082],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009100853,0.0001803479,0.00106202,0.0002240752,0.00001158914,0.00005066878,0.00003459466,0.00003321722,0.04355457,0.0001598957,0.00006031909,0.9545377],"study_design_scores_gemma":[0.002841162,0.001740464,0.0294429,0.00163155,0.0001511107,0.0001411473,0.00003130762,0.0002210899,0.007614988,0.00006649563,0.9547717,0.001346077],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0158147,0.9834506,0.00005786652,0.00009258531,0.0001947676,0.0002345441,0.00005731209,0.000004190219,0.00009345115],"genre_scores_gemma":[0.02321909,0.9748038,0.0000749619,0.000125838,0.00008526615,0.00003339868,0.0003066019,0.00001452833,0.001336496],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9547114,"threshold_uncertainty_score":0.8663065,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04139151068386539,"score_gpt":0.3386857704732331,"score_spread":0.2972942597893677,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}