{"id":"W2037713259","doi":"10.1111/j.1365-2141.2009.08027.x","title":"Alemtuzumab is safe and effective as immunosuppressive treatment for aplastic anaemia and single‐lineage marrow failure: a pilot study and a survey from the EBMT WPSAA","year":2009,"lang":"en","type":"article","venue":"British Journal of Haematology","topic":"Hematopoietic Stem Cell Transplantation","field":"Medicine","cited_by":75,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto","funders":"Università degli Studi di Napoli Federico II","keywords":"Alemtuzumab; Medicine; Regimen; Aplastic anemia; Bone marrow failure; Internal medicine; Pure red cell aplasia; Gastroenterology; Adverse effect; Aplasia; Immunology; Bone marrow; Toxicity; Immunosuppression; Oncology; Transplantation; Stem cell; Haematopoiesis; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006909618,0.0002358966,0.0003603844,0.0002367413,0.0002210087,0.0003240671,0.0001070018,0.0001955518,0.0005687675],"category_scores_gemma":[0.001032527,0.00009321373,0.0002449025,0.0002937255,0.0002589908,0.0001762793,0.0001075313,0.0001979519,0.0001379571],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001314846,"about_ca_system_score_gemma":0.000219763,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003404204,"about_ca_topic_score_gemma":0.0003788538,"domain_scores_codex":[0.9997175,0.0001244095,0.00002945092,0.00002671256,0.0000681306,0.0000336846],"domain_scores_gemma":[0.999638,0.0001701658,0.00007894103,0.00001998597,0.0000335231,0.00005945509],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.01497105,0.006178256,0.515821,0.0005147972,0.0005400573,0.006614652,0.0016074,0.0009967188,0.07643787,0.000356635,0.001023621,0.3749379],"study_design_scores_gemma":[0.003037863,0.107667,0.8445516,0.0000754206,0.0006399169,0.01797036,0.0004994128,0.001120531,0.01308611,0.0002313924,0.01108919,0.00003120748],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975101,0.001808468,0.0001489606,0.00005079151,0.00000348198,0.0000200911,0.00002221504,0.000003671659,0.0004322216],"genre_scores_gemma":[0.9985252,0.001056398,0.0001027994,0.0000609381,0.00001824518,0.00001470781,0.00006197187,0.000001343822,0.0001584747],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006909618,"threshold_uncertainty_score":0.003654242,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02306517286617608,"score_gpt":0.2834789399436454,"score_spread":0.2604137670774693,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}