{"id":"W2037745082","doi":"10.1016/s0143-4160(02)00207-5","title":"Mechanism of action of the novel plasma membrane Ca2+-pump inhibitor caloxin","year":2003,"lang":"en","type":"article","venue":"Cell Calcium","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University","funders":"","keywords":"Chemistry; Calmodulin; Extracellular; Biophysics; Cytosol; Intracellular; ATPase; Diaphragm pump; Activator (genetics); Biochemistry; Calcium pump; Binding site; Membrane; Peptide; Enzyme; Receptor; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001133884,0.00008145777,0.00009029161,0.00002576394,0.00003996992,0.000002975694,0.00006751377,0.0001430249,0.00004681219],"category_scores_gemma":[0.00004339981,0.00006317043,0.00009237736,0.00008724978,0.00004389313,0.000002475759,0.00002475627,0.00005278282,0.000003354187],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001105452,"about_ca_system_score_gemma":0.0000548315,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001296706,"about_ca_topic_score_gemma":0.000007637258,"domain_scores_codex":[0.9994261,0.00003867907,0.0001720394,0.0001425327,0.0001225488,0.00009812747],"domain_scores_gemma":[0.9995454,0.000006515418,0.0001175156,0.0002052905,0.0000937069,0.00003155437],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003389195,0.0000643143,0.00002775035,0.00003153108,0.000008408691,6.029652e-8,0.00002972236,0.0003206343,0.9979107,0.00112908,0.000388934,0.00005495906],"study_design_scores_gemma":[0.0005237482,0.00007427726,0.0000767942,0.000006031833,0.00001266964,0.000004321738,0.00009924432,0.0004064936,0.9856963,0.00003575677,0.01299772,0.00006662046],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9815652,0.0000311053,0.01269647,0.00005103848,0.001421755,0.0001459508,0.00001532637,0.000005301325,0.004067871],"genre_scores_gemma":[0.9963202,0.000009582337,0.0001238634,0.00005138215,0.0001370779,0.000004929691,0.00002072722,0.00001106411,0.003321197],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.014755,"threshold_uncertainty_score":0.2576015,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02390655883307212,"score_gpt":0.2407449594907558,"score_spread":0.2168384006576837,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}