{"id":"W2037828336","doi":"10.1242/dev.00987","title":"<i>C. elegans</i>SUR-6/PR55 cooperates with LET-92/protein phosphatase 2A and promotes Raf activity independently of inhibitory Akt phosphorylation sites","year":2004,"lang":"en","type":"article","venue":"Development","topic":"Genetics, Aging, and Longevity in Model Organisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":50,"is_retracted":false,"has_abstract":true,"ca_institutions":"Simon Fraser University","funders":"National Cancer Institute","keywords":"Protein phosphatase 2; Biology; Phosphorylation; Phosphatase; Protein subunit; MAPK/ERK pathway; Protein kinase B; Mutant; Kinase; Cell biology; Signal transduction; Suppressor; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000765701,0.0005273942,0.0001794328,0.0002116382,0.0002305373,0.0003167291,0.0002876809,0.0002266763,0.001946384],"category_scores_gemma":[0.00005645318,0.0001712615,0.0002857628,0.00007419557,0.0002312799,0.0001938777,0.0002826454,0.0004819914,0.0006713188],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003833548,"about_ca_system_score_gemma":0.0001778759,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001227114,"about_ca_topic_score_gemma":0.002963757,"domain_scores_codex":[0.9998554,0.00001126231,0.00001157238,0.00003661525,0.00004725923,0.0000379739],"domain_scores_gemma":[0.9999071,0.00000932627,0.00002721763,0.00001293087,0.000008385438,0.00003511112],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005794022,0.00001226222,0.0001452753,0.00002203109,0.000003301846,0.00005214657,0.00000394422,0.00004067485,0.9988639,0.00009674553,0.0000849792,0.0006166905],"study_design_scores_gemma":[0.000009165206,0.0001057523,0.003759889,0.00000498615,0.000008396377,0.0002547468,0.00001414365,0.000719255,0.9921665,0.00002768772,0.002925138,0.000004430931],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9881476,0.001145379,0.002578976,0.0002450549,0.00005351233,0.00002869733,0.0008761508,0.000349098,0.006575636],"genre_scores_gemma":[0.9898368,0.0004930753,0.003307445,0.00008386258,0.000009112347,0.00002465962,0.0009459979,0.00005828034,0.005240906],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001946384,"threshold_uncertainty_score":0.006511331,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007555284996590477,"score_gpt":0.1950465887012326,"score_spread":0.1874913037046421,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}