{"id":"W2037835662","doi":"10.1034/j.1399-3011.2002.21024.x","title":"An artificial peptide with corticotropin‐releasing factor receptor‐2 (CRF‐R2) selective properties: the role of primary structure in the induction of signal transduction pathways","year":2002,"lang":"en","type":"article","venue":"Journal of Peptide Research","topic":"Stress Responses and Cortisol","field":"Neuroscience","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Chinese hamster ovary cell; Biology; Receptor; Peptide sequence; Peptide; Biochemistry; Gene; Urocortin; Molecular biology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001648461,0.0001491508,0.000302107,0.0003601129,0.0002490127,0.00008851361,0.0005362183,0.00009227185,0.000193287],"category_scores_gemma":[0.0003941173,0.00007712129,0.0001032842,0.001001561,0.0004793905,0.0004778431,0.00002417236,0.001228551,0.000001728632],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001706283,"about_ca_system_score_gemma":0.0002814974,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001263806,"about_ca_topic_score_gemma":0.00007679478,"domain_scores_codex":[0.9954212,0.001634433,0.0006424703,0.0002391374,0.001688063,0.0003746387],"domain_scores_gemma":[0.9982466,0.0004099167,0.000457288,0.0002657229,0.0005439377,0.00007653976],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001961869,0.0002858828,0.001115484,0.00003179321,0.00001479901,0.00001309892,0.009988941,0.0007943314,0.9328883,0.00007739505,0.00003387131,0.05279429],"study_design_scores_gemma":[0.0004441423,0.003225968,0.02122028,0.0002026934,0.00001670492,0.0002703534,0.01187152,0.001119573,0.9608356,0.0004605011,0.000219532,0.0001130915],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9985005,0.0004584756,0.00007181819,0.0002955393,0.00006014855,0.0004236206,0.00001867361,0.000005375766,0.0001659093],"genre_scores_gemma":[0.9984711,0.001113719,0.00008330675,0.00002073663,0.0002599896,0.000008596008,4.886227e-7,0.00002006163,0.00002200172],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05268119,"threshold_uncertainty_score":0.533751,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1120866629160899,"score_gpt":0.3058976991509609,"score_spread":0.1938110362348711,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}