{"id":"W2037838520","doi":"10.1016/s0002-9440(10)63970-3","title":"Evidence that Furin Is an Authentic Transforming Growth Factor-β1-Converting Enzyme","year":2001,"lang":"en","type":"article","venue":"American Journal Of Pathology","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":242,"is_retracted":false,"has_abstract":false,"ca_institutions":"Montreal Clinical Research Institute; Université de Sherbrooke","funders":"Medical Research Council; Medical Research Council Canada; Arthritis Society","keywords":"Furin; Enzyme; Transforming growth factor; Chemistry; Biochemistry; Biology; Cell biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003065957,0.000185291,0.0003142948,0.0001111246,0.00008197884,0.00002142574,0.0004073447,0.00007839082,0.0000937232],"category_scores_gemma":[0.0002403509,0.0001669213,0.000181686,0.0001202131,0.0002510232,0.00002761423,0.00004297881,0.0001832491,0.000007867335],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002261559,"about_ca_system_score_gemma":0.0001408482,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001598728,"about_ca_topic_score_gemma":0.00000655631,"domain_scores_codex":[0.9985359,0.0002219283,0.0004190628,0.0002732654,0.000199932,0.0003499557],"domain_scores_gemma":[0.9987321,0.00005435706,0.0005972721,0.00025391,0.0001570606,0.0002052947],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003312507,0.000129908,0.08407292,0.000018137,0.00008485482,0.0005803445,0.002112542,0.00001854515,0.8639942,0.000009270477,0.00006184001,0.04858623],"study_design_scores_gemma":[0.000993101,0.004628951,0.0471198,0.000238237,0.0001674852,0.005731104,0.002825573,0.00005826874,0.9351253,0.0001965793,0.002288763,0.000626836],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.987327,0.0017459,0.01044624,0.0002163787,0.0001514425,0.00005841365,0.000005701777,0.00001041869,0.00003845978],"genre_scores_gemma":[0.9974579,0.000424282,0.001015378,0.0007289813,0.0002931787,0.000002879978,0.000003759897,0.00002927409,0.00004432609],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07113114,"threshold_uncertainty_score":0.6806855,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03255472035222865,"score_gpt":0.2897995962665573,"score_spread":0.2572448759143287,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}