{"id":"W2037870947","doi":"10.1371/journal.pone.0054728","title":"From Principle to Practice: Bridging the Gap in Patient Profiling","year":2013,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Blood Coagulation and Thrombosis Mechanisms","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier Universitaire Sainte-Justine","funders":"National Heart, Lung, and Blood Institute; U.S. Public Health Service; National Institutes of Health","keywords":"Thrombin; Thrombin generation; Partial thromboplastin time; Thrombin time; Prothrombin time; Medicine; Tissue factor; Discovery and development of direct thrombin inhibitors; Bioinformatics; Coagulation; Biomedical engineering; Computer science; Internal medicine; Biology; Platelet","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.03246385,0.001469232,0.001338677,0.002859225,0.002552452,0.01231939,0.004209375,0.005975397,0.01119681],"category_scores_gemma":[0.08681762,0.001320521,0.001251603,0.002512454,0.008175856,0.01565988,0.01793449,0.007609589,0.004313117],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003277252,"about_ca_system_score_gemma":0.007018362,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00257667,"about_ca_topic_score_gemma":0.002990954,"domain_scores_codex":[0.96556,0.02491251,0.001147005,0.003422069,0.00414819,0.0008101313],"domain_scores_gemma":[0.9560416,0.02896902,0.001694415,0.007612391,0.003360401,0.002322297],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004230479,0.00023593,0.0134922,0.001253253,0.0001577962,0.001080931,0.01727246,0.008448453,0.001993587,0.2839922,0.07132979,0.6003204],"study_design_scores_gemma":[0.0001187008,0.0002096778,0.002686478,0.001462133,0.00008476478,0.001705021,0.005960608,0.03991145,0.001683825,0.6517074,0.2943045,0.0001652961],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.01266185,0.006340731,0.8170035,0.128498,0.001306738,0.0004890893,0.0005264925,0.002475797,0.03069771],"genre_scores_gemma":[0.2212932,0.005860195,0.7473029,0.01652502,0.001108969,0.001019992,0.0006583824,0.001610758,0.004620518],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.03246385,"threshold_uncertainty_score":0.1716873,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06670049611702734,"score_gpt":0.2972658272593573,"score_spread":0.23056533114233,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}