{"id":"W2037901829","doi":"10.1139/y05-123","title":"Enhanced expression of Giα protein and adenylyl cyclase signaling in aortas from 1 kidney 1 clip hypertensive ratsThis paper is one of a selection of papers published in this Special issue, entitled Second Messengers and Phosphoproteins—12th International Conference.","year":2006,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Protein Kinase Regulation and GTPase Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Montreal Clinical Research Institute","funders":"","keywords":"Internal medicine; Endocrinology; Adenylyl cyclase; G protein; Forskolin; Angiotensin II; Chemistry; Kidney; Renin–angiotensin system; Guanosine; Gs alpha subunit; Receptor; Blood pressure; Medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001315359,0.0005553921,0.0007619555,0.0006272825,0.0003300923,0.0004473094,0.0002140495,0.0004087377,0.00297357],"category_scores_gemma":[0.0001214096,0.000342989,0.0004652111,0.0002883911,0.0003321217,0.0003261912,0.0002723662,0.001681552,0.0004461239],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000428043,"about_ca_system_score_gemma":0.0002901116,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001308624,"about_ca_topic_score_gemma":0.002134713,"domain_scores_codex":[0.9997862,0.000008737716,0.00001119051,0.00006690006,0.00005227721,0.00007459967],"domain_scores_gemma":[0.9997303,0.00001655642,0.00007726737,0.00002028409,0.00002854218,0.0001272024],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002465455,0.00003587556,0.000202938,0.00003074352,0.000008223034,0.00006364522,0.00002272992,0.000008978473,0.9987527,0.0000246137,0.00003961859,0.0005633223],"study_design_scores_gemma":[0.00008667135,0.001199265,0.1448856,0.0000266661,0.0001240712,0.001039858,0.000235572,0.0006030884,0.849104,0.00008311669,0.002577099,0.00003496293],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.996649,0.0007882258,0.0008086393,0.0001500459,0.0000969986,0.00001999914,0.0006926319,0.00006492236,0.0007296271],"genre_scores_gemma":[0.9830662,0.002312533,0.002128965,0.000249881,0.0001080643,0.00007548175,0.002467992,0.00006901559,0.009521921],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00297357,"threshold_uncertainty_score":0.009947538,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006826496320347153,"score_gpt":0.2270357812443102,"score_spread":0.2202092849239631,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}