{"id":"W2037984327","doi":"10.1089/109662003322233459","title":"Lycopene I—Effect on Osteoclasts: Lycopene Inhibits Basal and Parathyroid Hormone-Stimulated Osteoclast Formation and Mineral Resorption Mediated by Reactive Oxygen Species in Rat Bone Marrow Cultures","year":2003,"lang":"en","type":"article","venue":"Journal of Medicinal Food","topic":"Antioxidant Activity and Oxidative Stress","field":"Medicine","cited_by":92,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; St. Michael's Hospital","funders":"Natural Sciences and Engineering Research Council of Canada; Eli Lilly Canada","keywords":"Osteoclast; Chemistry; Resorption; Lycopene; Acid phosphatase; Multinucleate; Bone resorption; Parathyroid hormone; Internal medicine; Reactive oxygen species; Endocrinology; Ascorbic acid; Calcium; Biochemistry; Antioxidant; Cell biology; Biology; Medicine; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001075708,0.0003415316,0.0008244832,0.0004219787,0.0001136668,0.00004431975,0.00006689071,0.0002195969,0.00002855898],"category_scores_gemma":[0.001181683,0.0002413473,0.00008302055,0.0003598304,0.000199386,0.0007815395,0.00002890977,0.0007636257,0.000004135856],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001799413,"about_ca_system_score_gemma":0.00008485612,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001163843,"about_ca_topic_score_gemma":0.00005163491,"domain_scores_codex":[0.9974967,0.0004386009,0.0007331215,0.0002748465,0.0007300478,0.0003267392],"domain_scores_gemma":[0.9982953,0.0004585001,0.0005908296,0.0001251125,0.0002324911,0.0002977486],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.008602276,0.0002607207,0.00202077,0.00009765954,0.0001156299,0.0002555648,0.001107881,0.00001168667,0.9791754,0.00006228702,0.006948486,0.001341576],"study_design_scores_gemma":[0.04019281,0.04507241,0.1367806,0.002710081,0.0005273587,0.004209664,0.004252315,0.0003001597,0.7575318,0.000165398,0.007579654,0.000677867],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9915931,0.004909161,0.00007736357,0.001666521,0.0001219651,0.0005322744,0.0000271268,0.00001274442,0.001059709],"genre_scores_gemma":[0.9980501,0.001008138,0.0001245338,0.0003043282,0.0001741753,0.000006582459,0.0000682444,0.00002348192,0.0002404313],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2216437,"threshold_uncertainty_score":0.9841858,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01278449090553436,"score_gpt":0.2541061395949621,"score_spread":0.2413216486894277,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}