{"id":"W2037984327","doi":"10.1089/109662003322233459","title":"Lycopene I—Effect on Osteoclasts: Lycopene Inhibits Basal and Parathyroid Hormone-Stimulated Osteoclast Formation and Mineral Resorption Mediated by Reactive Oxygen Species in Rat Bone Marrow Cultures","year":2003,"lang":"en","type":"article","venue":"Journal of Medicinal Food","topic":"Antioxidant Activity and Oxidative Stress","field":"Medicine","cited_by":92,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; St. Michael's Hospital","funders":"Natural Sciences and Engineering Research Council of Canada; Eli Lilly Canada","keywords":"Osteoclast; Chemistry; Resorption; Lycopene; Acid phosphatase; Multinucleate; Bone resorption; Parathyroid hormone; Internal medicine; Reactive oxygen species; Endocrinology; Ascorbic acid; Calcium; Biochemistry; Antioxidant; Cell biology; Biology; Medicine; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001605304,0.000389952,0.0003069086,0.0001677338,0.0000901602,0.00019619,0.0002025334,0.000299937,0.001298863],"category_scores_gemma":[0.0001394285,0.00009453606,0.0002498792,0.0001109391,0.0001929966,0.000145996,0.0001399868,0.000596503,0.0003223652],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001223909,"about_ca_system_score_gemma":0.0002857758,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007181701,"about_ca_topic_score_gemma":0.001297619,"domain_scores_codex":[0.9999285,0.00001214473,0.000009555328,0.00001176983,0.00002158981,0.00001652569],"domain_scores_gemma":[0.9998455,0.00003592135,0.0000376202,0.00001137565,0.00001961122,0.00004978969],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002121253,0.0000571706,0.0001647326,0.00006522789,0.000005293948,0.00004057414,0.000009525244,0.00002335646,0.9984434,0.0000117938,0.00002226566,0.0009446429],"study_design_scores_gemma":[0.0001354089,0.00214508,0.007078593,0.00002812499,0.00003175363,0.0002691745,0.00003038393,0.000282413,0.9883188,0.00003754137,0.001638676,0.000004012509],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9865702,0.008547559,0.002611342,0.000111354,0.00003111494,0.0000683319,0.0004217315,0.0001041366,0.001534167],"genre_scores_gemma":[0.9872063,0.005422214,0.002912012,0.0001040957,0.00002591986,0.00005986714,0.001119508,0.00002319103,0.003126814],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001298863,"threshold_uncertainty_score":0.004345179,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01278449090553436,"score_gpt":0.2541061395949621,"score_spread":0.2413216486894277,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}