{"id":"W2038015440","doi":"10.1016/j.toxlet.2004.04.009","title":"Suppression of aromatase activity in vitro by PCBs 28 and 105 and Aroclor 1221","year":2004,"lang":"en","type":"article","venue":"Toxicology Letters","topic":"Effects and risks of endocrine disrupting chemicals","field":"Environmental Science","cited_by":36,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Ottawa; Health Canada","funders":"","keywords":"Aromatase; Microsome; Chemistry; Cytochrome P450; In vitro; Aromatase inhibitor; Testosterone (patch); Reductase; Metabolism; Enzyme; Endocrinology; Internal medicine; Biochemistry; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009444963,0.00009329359,0.0001574833,0.00002142869,0.00003409684,0.000005375011,0.00007094987,0.00005246468,0.00004227796],"category_scores_gemma":[0.00002862334,0.00007659566,0.00001610545,0.00004856224,0.000316694,0.00009167946,0.0001281536,0.0001155962,0.00000613275],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003755245,"about_ca_system_score_gemma":0.000002061574,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002687536,"about_ca_topic_score_gemma":0.00001850176,"domain_scores_codex":[0.9993671,0.00003824493,0.0001023429,0.0002250783,0.00007100958,0.0001962101],"domain_scores_gemma":[0.9996852,0.00009559261,0.00005241766,0.0001055927,7.677938e-7,0.00006047234],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005850359,0.00009449532,0.007628693,0.00001300364,0.000003113158,0.0000196393,0.000077141,0.00004275451,0.988269,0.00000172371,0.001605899,0.002186067],"study_design_scores_gemma":[0.0008468206,0.00005983857,0.03479712,0.0000129633,0.000006639178,0.00001614448,0.00001226225,0.00002863082,0.9633947,0.00007566292,0.0006515788,0.00009766406],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9958555,0.00004217901,0.0000129059,0.003774823,0.00002685735,0.0001152375,0.00001618434,0.00001038491,0.0001459452],"genre_scores_gemma":[0.9985996,0.00003025323,0.0004675603,0.0008649856,0.000007765207,0.000007444403,0.000006215969,0.000005778817,0.0000104141],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02716843,"threshold_uncertainty_score":0.3123481,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00508397687619995,"score_gpt":0.277989268567455,"score_spread":0.272905291691255,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}