{"id":"W2038039689","doi":"10.1210/en.2008-0581","title":"Variation in Kisspeptin and RFamide-Related Peptide (RFRP) Expression and Terminal Connections to Gonadotropin-Releasing Hormone Neurons in the Brain: A Novel Medium for Seasonal Breeding in the Sheep","year":2008,"lang":"en","type":"article","venue":"Endocrinology","topic":"Hypothalamic control of reproductive hormones","field":"Medicine","cited_by":374,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","keywords":"Kisspeptin; Internal medicine; Endocrinology; Biology; Hypothalamus; Seasonal breeder; Neuropeptide; Gonadotropin-releasing hormone; Hormone; Luteinizing hormone; Sex steroid; Receptor; Steroid; Ecology; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003389588,0.0001786965,0.0003262029,0.0003339922,0.0001461749,0.00001621715,0.0001257749,0.00008075934,0.00000479057],"category_scores_gemma":[0.001543878,0.0001275125,0.00003850967,0.0002919565,0.0001728463,0.0001127272,0.00006851916,0.0004713981,0.000001836086],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007409936,"about_ca_system_score_gemma":0.00006992148,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003150369,"about_ca_topic_score_gemma":0.0002463737,"domain_scores_codex":[0.9983638,0.0002006902,0.0003615316,0.0004698302,0.0001772653,0.0004269118],"domain_scores_gemma":[0.9985335,0.001045628,0.00008219852,0.0002365397,0.00004899406,0.00005307302],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.001198005,0.0004832103,0.06730573,0.00004096077,0.0000395216,0.000568398,0.01900655,0.0001309301,0.9031451,0.002280599,0.0007983823,0.005002565],"study_design_scores_gemma":[0.004622996,0.0005487495,0.9860478,0.00005351768,0.00002659606,0.004412655,0.001199756,0.001164881,0.0001434489,0.0001904067,0.001470977,0.000118229],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9458056,0.0006005427,0.0006452616,0.05153045,0.0000901069,0.001149338,0.000006416529,0.0000217528,0.0001505466],"genre_scores_gemma":[0.9972335,0.0001146718,0.0009788758,0.001204522,0.0001703513,0.0002015847,0.00000773139,0.00001800047,0.00007073502],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.9187421,"threshold_uncertainty_score":0.5199808,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03012171318084436,"score_gpt":0.2763468128498854,"score_spread":0.2462250996690411,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}