{"id":"W2038063394","doi":"10.1002/eji.201141879","title":"HMGB1 blockade attenuates experimental autoimmune myocarditis and suppresses Th17‐cell expansion","year":2011,"lang":"en","type":"article","venue":"European Journal of Immunology","topic":"NF-κB Signaling Pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":81,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lawson Health Research Institute; Western University","funders":"Natural Science Research of Jiangsu Higher Education Institutions of China; Government of Jiangsu Province; National Natural Science Foundation of China","keywords":"HMGB1; Blockade; Myocarditis; Autoimmunity; Immunology; Pathogenesis; Viral Myocarditis; Dilated cardiomyopathy; Heart failure; Biology; Monoclonal antibody; Inflammation; Medicine; Antibody; Receptor; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003872199,0.0001884709,0.0002441083,0.00008371219,0.0000865266,0.00001892832,0.0003378339,0.00006981585,0.00008792869],"category_scores_gemma":[0.00005864225,0.0001670253,0.0001207333,0.00004207132,0.0002249572,0.00001097106,0.0002554077,0.0002132528,0.00002841831],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000009570083,"about_ca_system_score_gemma":0.00004313985,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006267865,"about_ca_topic_score_gemma":2.894307e-7,"domain_scores_codex":[0.9985769,0.0004324006,0.0004277895,0.0002162151,0.0001000965,0.0002466477],"domain_scores_gemma":[0.9991984,0.00001703288,0.0003176171,0.0002883726,0.0001116839,0.00006682903],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000201498,0.0001173076,0.0005139976,0.000005496043,0.0001255204,0.0002274405,0.0006538608,0.000004101557,0.9956406,0.000007716237,0.0008445914,0.001657826],"study_design_scores_gemma":[0.001181328,0.001885698,0.01398686,0.00003401535,0.00003167629,0.001074302,0.0005491517,0.000001141351,0.9712378,0.00001627068,0.009823862,0.0001778993],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9709485,0.02503481,0.0002585742,0.00004132255,0.0004938809,0.00005576848,0.000006190925,0.00001122649,0.003149782],"genre_scores_gemma":[0.9970698,0.0008691016,0.001518702,0.00009163263,0.0002093096,0.000001080607,0.00001049829,0.00004632212,0.0001835196],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02612139,"threshold_uncertainty_score":0.6811094,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0151208878588014,"score_gpt":0.2031242848104501,"score_spread":0.1880033969516487,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}