{"id":"W2038063394","doi":"10.1002/eji.201141879","title":"HMGB1 blockade attenuates experimental autoimmune myocarditis and suppresses Th17‐cell expansion","year":2011,"lang":"en","type":"article","venue":"European Journal of Immunology","topic":"NF-κB Signaling Pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":81,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lawson Health Research Institute; Western University","funders":"Natural Science Research of Jiangsu Higher Education Institutions of China; Government of Jiangsu Province; National Natural Science Foundation of China","keywords":"HMGB1; Blockade; Myocarditis; Autoimmunity; Immunology; Pathogenesis; Viral Myocarditis; Dilated cardiomyopathy; Heart failure; Biology; Monoclonal antibody; Inflammation; Medicine; Antibody; Receptor; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003080807,0.0007004721,0.0006900366,0.0003948251,0.0002252539,0.0002893672,0.0002909637,0.0004121582,0.001487442],"category_scores_gemma":[0.0001925359,0.00021567,0.0003127679,0.0001461775,0.0004624832,0.0002892188,0.0001789242,0.001504514,0.0003841],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001865474,"about_ca_system_score_gemma":0.0003503012,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002715906,"about_ca_topic_score_gemma":0.0006654188,"domain_scores_codex":[0.9997938,0.00005355441,0.00001758836,0.00002018124,0.00003948689,0.00007530806],"domain_scores_gemma":[0.9997653,0.00003167196,0.00006217547,0.00002297445,0.00001688742,0.0001009338],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002960661,0.001070569,0.0003835633,0.000156844,0.00003493228,0.000114441,0.00004427235,0.000143526,0.989861,0.000157911,0.0001684242,0.004903845],"study_design_scores_gemma":[0.001039178,0.01237083,0.007795262,0.00004321437,0.0001066454,0.0002824857,0.00009912691,0.001619094,0.9736951,0.0001958753,0.002738657,0.00001447475],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9957626,0.002334802,0.0006596975,0.0001576641,0.0000898408,0.00003121087,0.0001127965,0.0001075156,0.0007437538],"genre_scores_gemma":[0.9945195,0.001750213,0.0009733717,0.0001165565,0.00008157772,0.00007763235,0.0002957522,0.00002738977,0.002158011],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001487442,"threshold_uncertainty_score":0.004975975,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0151208878588014,"score_gpt":0.2031242848104501,"score_spread":0.1880033969516487,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}