{"id":"W2038082991","doi":"10.18388/abp.2001_3884","title":"A novel cis-peptide bond motif inducing beta-turn type VI. The synthesis of enkephalin analogues modified with 4-aminopyroglutamic acid.","year":2001,"lang":"en","type":"article","venue":"Acta Biochimica Polonica","topic":"Chemical Synthesis and Analysis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Clinical Research Institute","funders":"Heart And Stroke Foundation Of Quebec; Heart and Stroke Foundation of Canada","keywords":"Chemistry; Stereochemistry; Peptide; Hydrolysis; Enkephalin; Decarboxylation; Turn (biochemistry); Peptide bond; Biochemistry; Catalysis; Opioid; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008947604,0.0004043948,0.0002196227,0.0001456396,0.0001075004,0.0002474342,0.0002600634,0.0002826184,0.001080476],"category_scores_gemma":[0.0001068972,0.0001853003,0.0002442806,0.0001252754,0.0001341488,0.0002153544,0.0001901147,0.0004314797,0.0007533844],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001569473,"about_ca_system_score_gemma":0.0001087267,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001448763,"about_ca_topic_score_gemma":0.000210703,"domain_scores_codex":[0.9999369,0.00001051767,0.000005365279,0.00001655214,0.00001442661,0.00001622187],"domain_scores_gemma":[0.9999291,0.000005902836,0.00002737802,0.000007144012,0.000008280847,0.00002224539],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007586951,0.0000116197,0.00005370839,0.00004448113,0.000004772017,0.00009981337,0.000008638435,0.00009004196,0.9968991,0.0001626652,0.00002971971,0.00251963],"study_design_scores_gemma":[0.0000178395,0.0003789277,0.0005415301,0.000004271199,0.00001668621,0.0006201918,0.000007092559,0.0002244075,0.992134,0.00005236621,0.005996308,0.000006449227],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9568265,0.004623046,0.03010901,0.000131871,0.0001453626,0.0002509135,0.0006813247,0.0004038542,0.006828211],"genre_scores_gemma":[0.9602251,0.002191761,0.02859659,0.00008722061,0.00002932925,0.0001191355,0.0008435314,0.0000663771,0.007841093],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001080476,"threshold_uncertainty_score":0.003614604,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01606260527567031,"score_gpt":0.2366771646117811,"score_spread":0.2206145593361108,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}