{"id":"W2038085623","doi":"10.1016/j.ijpara.2010.02.004","title":"LmxMPK4, an essential mitogen-activated protein kinase of Leishmania mexicana is phosphorylated and activated by the STE7-like protein kinase LmxMKK5","year":2010,"lang":"en","type":"article","venue":"International Journal for Parasitology","topic":"Research on Leishmaniasis Studies","field":"Medicine","cited_by":23,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Syddansk Universitet; Wellcome Trust; Ryerson University","keywords":"MAP2K7; Mitogen-activated protein kinase kinase; Biology; Cyclin-dependent kinase 2; c-Raf; Protein kinase A; Molecular biology; Biochemistry; MAPK14; Leishmania mexicana; Cyclin-dependent kinase 9; MAP kinase kinase kinase; Phosphotransferase; Kinase; Staurosporine; Phosphorylation; Leishmania","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001199997,0.0003997234,0.000173824,0.0002299996,0.0003485325,0.0002868836,0.000194233,0.0002691898,0.00234299],"category_scores_gemma":[0.0001412539,0.0001677017,0.0003476214,0.0001134795,0.0001706393,0.0003009745,0.0002862844,0.0003197415,0.0005868775],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003490273,"about_ca_system_score_gemma":0.0001596986,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004686328,"about_ca_topic_score_gemma":0.0005189662,"domain_scores_codex":[0.9999257,0.00001845224,0.000005081621,0.00001484118,0.000013421,0.00002237167],"domain_scores_gemma":[0.999945,0.000007409231,0.00002030005,0.00000540229,0.00000754681,0.00001431954],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006582644,0.00001994257,0.000623916,0.00007236969,0.000009193081,0.0001127893,0.0000172607,0.0001060806,0.9968407,0.0002096946,0.00007239288,0.001257496],"study_design_scores_gemma":[0.00005563919,0.0002515531,0.02491473,0.0000126703,0.00002488927,0.0008366647,0.0001102443,0.002769154,0.9662602,0.000287698,0.004463999,0.00001259793],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9951179,0.0008607613,0.001862871,0.0000989021,0.00002028702,0.00001819746,0.0003476606,0.00005171472,0.001621714],"genre_scores_gemma":[0.9946531,0.000365818,0.00140589,0.00002625926,0.000008164514,0.00001792395,0.001275835,0.00001391328,0.002233017],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00234299,"threshold_uncertainty_score":0.00783813,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01997453850184923,"score_gpt":0.3591955161810981,"score_spread":0.3392209776792489,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}