{"id":"W2038088649","doi":"10.1016/j.neuroscience.2015.02.034","title":"Lysophosphatidylcholine increases the neurotoxicity of Alzheimer’s amyloid β1-42 peptide: Role of oligomer formation","year":2015,"lang":"en","type":"article","venue":"Neuroscience","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":54,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia Hospital","funders":"Japan Society for the Promotion of Science","keywords":"Lysophosphatidylcholine; Viability assay; Molecular biology; Blot; Oligomer; Chemistry; Apoptosis; Terminal deoxynucleotidyl transferase; Neurotoxicity; Lactate dehydrogenase; TUNEL assay; Biology; Biochemistry; Toxicity; Enzyme; Phosphatidylcholine; Phospholipid","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001701827,0.0004750503,0.0002875792,0.0003191187,0.0001980778,0.0004263084,0.0002122171,0.0005714113,0.002205927],"category_scores_gemma":[0.0003838961,0.0002565271,0.0002924923,0.0001927357,0.000249763,0.0005359194,0.0003305133,0.0007651326,0.0004879857],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002653729,"about_ca_system_score_gemma":0.0004145739,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009930823,"about_ca_topic_score_gemma":0.001074826,"domain_scores_codex":[0.9998497,0.00003801006,0.00001345816,0.00002056121,0.00003422702,0.00004411027],"domain_scores_gemma":[0.9997571,0.00004633154,0.00004878406,0.00003155213,0.00004277928,0.00007348414],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.004776663,0.0003298809,0.0005963746,0.0001553988,0.00005132181,0.0004205402,0.00007694346,0.0001029883,0.9877731,0.0002667351,0.0002116818,0.005238281],"study_design_scores_gemma":[0.0001849201,0.001981577,0.01581007,0.00003896289,0.0001358321,0.0008118938,0.000141893,0.0007718683,0.9772636,0.0004805816,0.002363435,0.00001537188],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9942867,0.003299496,0.0006168648,0.0001764393,0.00005490678,0.00001649368,0.0001200099,0.0000442688,0.001384917],"genre_scores_gemma":[0.9930252,0.00311438,0.0004951606,0.00009018336,0.00003374839,0.00001942561,0.000216825,0.00001560201,0.0029894],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002205927,"threshold_uncertainty_score":0.007379591,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06718149926724169,"score_gpt":0.331630253291441,"score_spread":0.2644487540241993,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}