{"id":"W2038100682","doi":"10.1111/j.1572-0241.2004.04038.x","title":"CARD15 and HLA DRB1 Alleles Influence Susceptibility and Disease Localization in Crohn's Disease","year":2004,"lang":"en","type":"article","venue":"The American Journal of Gastroenterology","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":107,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Canadian Arthritis Network; Canadian Institutes of Health Research; Arthritis Society","keywords":"Allele; Medicine; Genotyping; Crohn's disease; Inflammatory bowel disease; Human leukocyte antigen; Gastroenterology; Genetics; Disease; Genotype; Internal medicine; Immunology; Biology; Gene; Antigen","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004401963,0.0004149404,0.0002171904,0.0005778,0.0004978784,0.0005406775,0.0004190774,0.0005329826,0.003148591],"category_scores_gemma":[0.001729206,0.0001864694,0.0003796919,0.0009257222,0.0004855887,0.0001848323,0.0003371363,0.0003594854,0.0002940351],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005962506,"about_ca_system_score_gemma":0.0008746315,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.08548199,"about_ca_topic_score_gemma":0.08786205,"domain_scores_codex":[0.9996118,0.00008594866,0.00002383292,0.00009262872,0.00007780492,0.0001080415],"domain_scores_gemma":[0.9989427,0.0002180081,0.0003952801,0.00004664065,0.0001132113,0.0002842094],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0002912991,0.00001904664,0.9956826,0.00001229902,0.00005588975,0.0002350801,0.00009310069,0.00004103055,0.001259009,0.00002230303,0.00007516335,0.002213248],"study_design_scores_gemma":[0.000009038008,0.00003666851,0.9989851,0.00001053318,0.00004832536,0.0004671611,0.00007549657,0.000106616,0.0000818809,0.000019972,0.0001565921,0.000002563584],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9988065,0.0005323206,0.00005192939,0.00005638247,0.000004138665,0.000003954765,0.000103104,0.000003187678,0.0004384895],"genre_scores_gemma":[0.9994674,0.0001308294,0.00008346236,0.00001302025,0.000004262463,0.000001540355,0.00007835398,0.000001959811,0.0002191381],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08548199,"threshold_uncertainty_score":0.1699689,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003349532704783471,"score_gpt":0.2214202572465354,"score_spread":0.2180707245417519,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}