{"id":"W2038143616","doi":"10.1016/j.clinbiochem.2009.07.019","title":"Drugs of abuse testing by tandem mass spectrometry: A rapid, simple method to replace immunoassays","year":2009,"lang":"en","type":"article","venue":"Clinical Biochemistry","topic":"Forensic Toxicology and Drug Analysis","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":78,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Saskatchewan; Saskatchewan Disease Control Laboratory","funders":"","keywords":"Chromatography; Drugs of abuse; Immunoassay; Mass spectrometry; Tandem mass spectrometry; Chemistry; Liquid chromatography–mass spectrometry; Drug; Pharmacology; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.004122259,0.0003399827,0.0008644332,0.00009496189,0.0001965546,0.00001557437,0.0005837389,0.001055256,0.001446026],"category_scores_gemma":[0.00289398,0.000333562,0.0004010356,0.0009492398,0.0003786988,0.00004832291,0.00008154991,0.001421104,0.0001449442],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008312009,"about_ca_system_score_gemma":0.00014507,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001001711,"about_ca_topic_score_gemma":4.99914e-7,"domain_scores_codex":[0.9963508,0.0006961673,0.001276641,0.0008128705,0.0002244776,0.0006389977],"domain_scores_gemma":[0.9945133,0.003611281,0.0004840804,0.0006704897,0.000201689,0.0005191233],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005781479,0.0007914269,0.009498141,0.0000322765,0.0004476149,0.00002904141,0.0001694064,0.00006843577,0.8488504,0.0000565732,0.1045534,0.0349251],"study_design_scores_gemma":[0.002282093,0.0007697417,0.001004728,0.00002782672,0.0004351867,0.00002133743,0.0003779303,0.001125785,0.9537191,0.001486797,0.03824065,0.0005088634],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9731899,0.001198102,0.004390711,0.002403824,0.0003964554,0.0002944795,0.0001593886,0.0001896581,0.01777752],"genre_scores_gemma":[0.9634728,0.0001204618,0.02720053,0.006105798,0.0003672476,0.00001318318,0.00008429272,0.0000233427,0.002612366],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1048687,"threshold_uncertainty_score":0.9999117,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08305375378371022,"score_gpt":0.4706146358658287,"score_spread":0.3875608820821185,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}