{"id":"W2038165112","doi":"10.1016/j.molonc.2015.01.004","title":"RhoC and ROCKs regulate cancer cell interactions with endothelial cells","year":2015,"lang":"en","type":"article","venue":"Molecular Oncology","topic":"Protein Kinase Regulation and GTPase Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Biotechnology and Biological Sciences Research Council; Cancer Research UK; Vedecká Grantová Agentúra MŠVVaŠ SR a SAV; Royal Society; Cancer Research Society","keywords":"RhoC; ROCK1; Cancer cell; Cell biology; Cancer research; Metastasis; Biology; Cell adhesion; Cancer; Cell; RHOA; Chemistry; Signal transduction; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001265338,0.000249915,0.0001952232,0.0002638298,0.0003562825,0.0004035179,0.0001737461,0.0002367998,0.001393178],"category_scores_gemma":[0.0001125923,0.0001300661,0.0002495576,0.0001374393,0.0002567268,0.0001757024,0.0003314372,0.0005327259,0.0005371289],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003526041,"about_ca_system_score_gemma":0.0002362254,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006622807,"about_ca_topic_score_gemma":0.0008958072,"domain_scores_codex":[0.9998146,0.00003791246,0.000008914869,0.00002779683,0.00005439371,0.00005646447],"domain_scores_gemma":[0.9999208,0.000006630065,0.00002641417,0.000006498964,0.00001431967,0.00002529553],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002647038,0.00002404535,0.0009075221,0.00008430868,0.0000145518,0.0002679557,0.00004903118,0.0001882097,0.9916595,0.001306358,0.0005046388,0.0047293],"study_design_scores_gemma":[0.00004357976,0.0001310258,0.02894075,0.00002223952,0.00004807077,0.0008003269,0.0001260618,0.003672381,0.9384376,0.0005361166,0.02722508,0.00001675496],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9623837,0.01831826,0.006875287,0.000648121,0.00008643995,0.000056381,0.0008291866,0.0003482206,0.0104544],"genre_scores_gemma":[0.9882704,0.003063653,0.001656218,0.00008562968,0.00001732166,0.00004789593,0.0005365372,0.00003271238,0.006289693],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001393178,"threshold_uncertainty_score":0.004660606,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01316913190654258,"score_gpt":0.2727717460829026,"score_spread":0.25960261417636,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}