{"id":"W2038165112","doi":"10.1016/j.molonc.2015.01.004","title":"RhoC and ROCKs regulate cancer cell interactions with endothelial cells","year":2015,"lang":"en","type":"article","venue":"Molecular Oncology","topic":"Protein Kinase Regulation and GTPase Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Biotechnology and Biological Sciences Research Council; Cancer Research UK; Vedecká Grantová Agentúra MŠVVaŠ SR a SAV; Royal Society; Cancer Research Society","keywords":"RhoC; ROCK1; Cancer cell; Cell biology; Cancer research; Metastasis; Biology; Cell adhesion; Cancer; Cell; RHOA; Chemistry; Signal transduction; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001145375,0.0001474312,0.0001493225,0.00003231699,0.00005767454,0.0000188517,0.00008430321,0.0001301789,0.00004147679],"category_scores_gemma":[0.00001292179,0.000131945,0.00004107757,0.00005393706,0.00008777266,0.000005779832,0.00008473055,0.00009086202,0.000008244514],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004621239,"about_ca_system_score_gemma":0.0002319244,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001497944,"about_ca_topic_score_gemma":0.000391922,"domain_scores_codex":[0.9991274,0.00009756054,0.0001449251,0.0003150979,0.0001035325,0.0002114829],"domain_scores_gemma":[0.9994076,0.000006633477,0.00008938229,0.0002115011,0.0001122427,0.0001726713],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002866339,0.00005995147,0.00009938232,0.000008970821,0.00003772126,0.00004650465,0.00008990496,0.001296181,0.993473,0.00007837862,0.0008109875,0.003712399],"study_design_scores_gemma":[0.001152058,0.0005463567,0.00002407435,0.000008931554,0.00003049673,0.00006000354,0.00008123203,0.0002255303,0.7422537,0.00005127806,0.2554135,0.0001527928],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9627954,0.002732207,0.02329812,0.0006078574,0.000265083,0.0003415526,0.00003057945,0.00002951276,0.009899705],"genre_scores_gemma":[0.995219,0.0001040515,0.002340786,0.0006495542,0.0001496293,0.0000636685,0.00003675977,0.00002809927,0.001408441],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2546026,"threshold_uncertainty_score":0.538056,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01316913190654258,"score_gpt":0.2727717460829026,"score_spread":0.25960261417636,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}