{"id":"W2038167599","doi":"10.1371/journal.pone.0033333","title":"Regulation of Synaptic Vesicle Docking by Different Classes of Macromolecules in Active Zone Material","year":2012,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":69,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Neurological Disorders and Stroke; National Institute of Mental Health; Natural Sciences and Engineering Research Council of Canada; National Institutes of Health","keywords":"Vesicle; Synaptic vesicle; Active zone; Exocytosis; Docking (animal); Biophysics; Vesicle fusion; Macromolecule; Axon; Chemistry; Membrane; Biology; Cell biology; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001716819,0.0001670819,0.0002512304,0.0003874713,0.0002876864,0.000785752,0.0004062572,0.0003198607,0.0005630195],"category_scores_gemma":[0.0004062504,0.000257374,0.0003168816,0.0001609852,0.0005181691,0.000632914,0.0004127517,0.0003269656,0.0001844918],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005970636,"about_ca_system_score_gemma":0.0001927923,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005746104,"about_ca_topic_score_gemma":0.0007956715,"domain_scores_codex":[0.999816,0.00001772371,0.00001537323,0.00005534381,0.00005974724,0.00003588831],"domain_scores_gemma":[0.9995643,0.00009136067,0.0001344568,0.00004427893,0.00004646907,0.0001191713],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008162564,0.00001401916,0.00142096,0.00001810871,0.000005061728,0.00003161846,0.00003229378,0.0001183427,0.9973802,0.0001959192,0.000004328964,0.0006974587],"study_design_scores_gemma":[0.00001759314,0.0001680999,0.09675188,0.000008724499,0.00003078833,0.0002514302,0.0001240272,0.006724738,0.8948998,0.0002379102,0.0007652347,0.0000197077],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9981456,0.0003219073,0.00126935,0.000008229503,0.000002669752,0.000004942636,0.00001674194,0.00001205721,0.000218536],"genre_scores_gemma":[0.9982297,0.000159734,0.001179485,0.000006363054,0.000001978811,0.000008500898,0.00005045002,0.000008637262,0.0003550515],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000785752,"threshold_uncertainty_score":0.004332006,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01468378246758438,"score_gpt":0.204982578283883,"score_spread":0.1902987958162987,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}