{"id":"W2038171923","doi":"10.1074/jbc.m007944200","title":"Co-translational Interactions of Apoprotein B with the Ribosome and Translocon during Lipoprotein Assembly or Targeting to the Proteasome","year":2001,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Endoplasmic Reticulum Stress and Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":93,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"National Institute of General Medical Sciences; National Heart, Lung, and Blood Institute","keywords":"Endoplasmic reticulum; Apolipoprotein B; Proteasome; Microsomal triglyceride transfer protein; Translocon; Lipid-anchored protein; Cell biology; Biochemistry; Cytosol; Ribosome; Chemistry; Lipoprotein; Biology; Very low-density lipoprotein; Autophagy; Cholesterol; Membrane protein; Enzyme; RNA; Apoptosis; Gene; Membrane","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003338496,0.0002597396,0.0002940418,0.0001618864,0.0003558697,0.0005101606,0.0001999477,0.0002933773,0.0008836531],"category_scores_gemma":[0.00023813,0.0001779865,0.0002886367,0.0001517811,0.0002450408,0.000318911,0.000396203,0.000571351,0.001109476],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005386357,"about_ca_system_score_gemma":0.0003026575,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006171489,"about_ca_topic_score_gemma":0.0009781288,"domain_scores_codex":[0.9997322,0.00003653495,0.00002540367,0.00007728595,0.00007030198,0.00005824593],"domain_scores_gemma":[0.9998754,0.00001682562,0.00002349189,0.00002278683,0.00002310132,0.0000383957],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002596482,0.00002646989,0.0003338367,0.00003421293,0.000008769939,0.0001234633,0.00002132302,0.00002580506,0.9977601,0.0001648316,0.00008609984,0.001155438],"study_design_scores_gemma":[0.00004671719,0.0002198812,0.01219593,0.00001171724,0.00002024224,0.0006143449,0.00006675255,0.002034772,0.9805808,0.000142741,0.004054417,0.00001166673],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9899934,0.003988988,0.003750232,0.0001996994,0.0000784425,0.00001799634,0.0001486697,0.00005959623,0.001762902],"genre_scores_gemma":[0.991203,0.001051968,0.00281516,0.00009952141,0.00003909819,0.00003004846,0.0004810105,0.00003770949,0.004242458],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008836531,"threshold_uncertainty_score":0.003908098,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0127737561945532,"score_gpt":0.2611245165074052,"score_spread":0.248350760312852,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}