{"id":"W2038184258","doi":"10.1016/j.pnpbp.2012.05.014","title":"The role of brain-derived neurotrophic factor (BDNF) gene variants in antipsychotic response and antipsychotic-induced weight gain","year":2012,"lang":"en","type":"article","venue":"Progress in Neuro-Psychopharmacology and Biological Psychiatry","topic":"Nerve injury and regeneration","field":"Neuroscience","cited_by":73,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"Canadian Institutes of Health Research; Ontario Mental Health Foundation; National Alliance for Research on Schizophrenia and Depression; AstraZeneca; Eli Lilly and Company; American Foundation for Suicide Prevention","keywords":"Antipsychotic; Brain-derived neurotrophic factor; Neurotrophic factors; Weight gain; Schizophrenia (object-oriented programming); Neuroscience; Medicine; Psychology; Internal medicine; Pharmacology; Psychiatry; Body weight; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004248141,0.0005284962,0.0003662713,0.0006560736,0.0002772509,0.0004328237,0.000325515,0.0006266491,0.001447868],"category_scores_gemma":[0.001933235,0.0002416372,0.000549831,0.0005457542,0.0003747276,0.0002296555,0.0002587408,0.0006589037,0.0001197522],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000340755,"about_ca_system_score_gemma":0.0002880196,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005203184,"about_ca_topic_score_gemma":0.007248441,"domain_scores_codex":[0.9996225,0.0001298969,0.00005521455,0.0000749201,0.00007873183,0.00003873682],"domain_scores_gemma":[0.9988775,0.0004018046,0.0004934529,0.00006247298,0.00006007509,0.000104717],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.01092215,0.0002416928,0.892724,0.00009276567,0.001758145,0.00230181,0.0002834982,0.0007467835,0.07288416,0.0006206378,0.0002199656,0.01720444],"study_design_scores_gemma":[0.00005647631,0.0001714512,0.9960219,0.00001176069,0.0002320978,0.001059367,0.00004219011,0.0008758992,0.001113665,0.0002689695,0.0001335759,0.00001268661],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9985414,0.0007164056,0.0001700525,0.0001180476,0.000009739315,0.000003082656,0.0001457451,0.000004572764,0.000291059],"genre_scores_gemma":[0.9993591,0.0001693786,0.0002119003,0.0000302956,0.000008266212,0.000002452686,0.00006799785,0.000005503444,0.0001452545],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005203184,"threshold_uncertainty_score":0.01034582,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03189837808769757,"score_gpt":0.3202531541738444,"score_spread":0.2883547760861468,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}