{"id":"W2038188372","doi":"10.1099/mic.0.028969-0","title":"Burkholderia cenocepacia zinc metalloproteases influence resistance to antimicrobial peptides","year":2009,"lang":"en","type":"article","venue":"Microbiology","topic":"Antimicrobial Peptides and Activities","field":"Immunology and Microbiology","cited_by":57,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Proteases; Elafin; Microbiology; Protease; Antimicrobial peptides; Biology; Antimicrobial; Cathelicidin; Neutrophil elastase; Elastase; Biochemistry; Enzyme; Immunology; Inflammation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002552487,0.0005386244,0.0007799581,0.0002599176,0.0004599508,0.00006875911,0.0006637843,0.0004754385,0.0004475999],"category_scores_gemma":[0.0001523975,0.0005020702,0.0002478186,0.0003455842,0.0005121364,0.0002450824,0.0001816995,0.0004457576,0.002239816],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008854216,"about_ca_system_score_gemma":0.0001040387,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000114161,"about_ca_topic_score_gemma":0.0001526939,"domain_scores_codex":[0.9971371,0.0002360922,0.0006025407,0.000884783,0.00002756494,0.001111979],"domain_scores_gemma":[0.9988342,0.0001059495,0.0002160671,0.0005941463,0.0001684396,0.00008119682],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003364941,0.0001559839,0.0001977413,0.00001857284,0.00009774344,0.00002075718,0.0002492488,0.00003093528,0.9333116,0.001385881,0.06340089,0.0007940984],"study_design_scores_gemma":[0.0007946545,0.0003019383,0.003010911,0.0001043673,0.00004885131,0.0002693472,0.00009019548,9.924386e-8,0.758811,0.0002445571,0.2357034,0.0006206944],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9912692,0.0009624696,0.0002725988,0.00279367,0.0006299298,0.0006388713,0.0003308775,0.0003099974,0.002792371],"genre_scores_gemma":[0.980894,0.00006364755,0.0021613,0.006378939,0.0001053437,0.00001922301,0.000256257,0.000036648,0.01008462],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1745007,"threshold_uncertainty_score":0.9997431,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00894116660696047,"score_gpt":0.2265061325367603,"score_spread":0.2175649659297998,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}