{"id":"W2038217485","doi":"10.1016/j.peptides.2009.06.015","title":"Melanin-concentrating hormone induces neurite outgrowth in human neuroblastoma SH-SY5Y cells through p53 and MAPKinase signaling pathways","year":2009,"lang":"en","type":"article","venue":"Peptides","topic":"Regulation of Appetite and Obesity","field":"Neuroscience","cited_by":24,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hôpital Maisonneuve-Rosemont","funders":"","keywords":"Neurite; Melanin-concentrating hormone; CREB; Phosphorylation; Neuroblastoma; Signal transduction; Cell biology; SH-SY5Y; Biology; Protein kinase A; Endogeny; Endocrinology; Receptor; Internal medicine; Transcription factor; Cell culture; Neuropeptide; In vitro; Medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000165413,0.0003129755,0.0002768306,0.0003019693,0.0002914903,0.0002721767,0.0001512681,0.000233135,0.001174466],"category_scores_gemma":[0.0001001152,0.0001622364,0.0004699512,0.0001872647,0.0002010337,0.0002720978,0.0002566005,0.0007125016,0.0003480213],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005348545,"about_ca_system_score_gemma":0.0004025925,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004155249,"about_ca_topic_score_gemma":0.008032545,"domain_scores_codex":[0.9998872,0.00001401157,0.00001361108,0.000017263,0.00002703868,0.00004078111],"domain_scores_gemma":[0.9999151,0.00001944285,0.00001278951,0.00001343719,0.00001116634,0.00002802784],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002964909,0.00005876819,0.0002679318,0.00003560194,0.00001039958,0.0001643503,0.00002857596,0.00003654886,0.9979491,0.00007433801,0.0000875757,0.000990359],"study_design_scores_gemma":[0.00005980273,0.0005563699,0.02130036,0.00001487541,0.00003667946,0.0003806597,0.0001241015,0.001019301,0.9743022,0.00008541767,0.002112769,0.000007577794],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954261,0.001553841,0.0005171646,0.0001458218,0.0000443306,0.00001583592,0.0004198292,0.00003414416,0.001842861],"genre_scores_gemma":[0.9937209,0.001492522,0.0008639776,0.00005586593,0.00001374066,0.00004308459,0.0006782325,0.00001083345,0.003120802],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004155249,"threshold_uncertainty_score":0.008262098,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03229351257646237,"score_gpt":0.2553424248644754,"score_spread":0.223048912288013,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}