{"id":"W2038231474","doi":"10.1016/j.bej.2009.03.005","title":"Culture pH and osmolality influence proliferation and embryoid body yields of murine embryonic stem cells","year":2009,"lang":"en","type":"article","venue":"Biochemical Engineering Journal","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":45,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia; Canada's Michael Smith Genome Sciences Centre","funders":"Stem Cell Network","keywords":"Embryoid body; Embryonic stem cell; Glutamine; Stem cell; Osmole; Ammonium; Osmotic concentration; Chemistry; Osmotic pressure; Biochemistry; Cell culture; Biology; Cell biology; Biophysics; Andrology; Endocrinology; Amino acid; Adult stem cell","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000205388,0.0001401086,0.0001514157,0.00004387701,0.00004310131,0.00004191753,0.0001196241,0.0001760863,0.000002029643],"category_scores_gemma":[0.0000553158,0.000123197,0.0000443207,0.00006758813,0.00004217534,0.00001056533,0.00006731714,0.0002603158,5.231529e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001622859,"about_ca_system_score_gemma":0.00003960514,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":9.498679e-7,"about_ca_topic_score_gemma":8.589716e-8,"domain_scores_codex":[0.9991577,0.00002141602,0.0002175427,0.0002077192,0.0001769605,0.0002186934],"domain_scores_gemma":[0.9995062,0.000008263274,0.00006660532,0.0001398658,0.0001040266,0.0001749841],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004402041,0.00003124708,0.0003021494,0.00006568201,0.00002124717,0.000004468438,0.00002195164,0.0003614705,0.9984734,0.0000143035,0.0003263088,0.0003337362],"study_design_scores_gemma":[0.0004180049,0.0002654588,0.003776467,0.00005608337,0.00001099164,0.0001975534,0.00000951449,0.001171003,0.9932318,0.0000113983,0.0007128191,0.0001388925],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9957527,0.002557485,0.001389442,0.0001238238,0.00003782619,0.00009996176,0.000005886454,0.000008460848,0.00002444395],"genre_scores_gemma":[0.9979507,0.0008244344,0.0008824503,0.0000402618,0.000150901,0.000001980984,0.00000646608,0.000009380305,0.0001334246],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005241601,"threshold_uncertainty_score":0.5023828,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005383166681444586,"score_gpt":0.2252968447462314,"score_spread":0.2199136780647868,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}