{"id":"W2038284708","doi":"10.1038/onc.2012.507","title":"The differentiation stage of p53-Rb-deficient bone marrow mesenchymal stem cells imposes the phenotype of in vivo sarcoma development","year":2012,"lang":"en","type":"article","venue":"Oncogene","topic":"Sarcoma Diagnosis and Treatment","field":"Medicine","cited_by":94,"is_retracted":false,"has_abstract":false,"ca_institutions":"Health Canada","funders":"","keywords":"Mesenchymal stem cell; Biology; Cancer research; Progenitor cell; Bone marrow; Phenotype; Sarcoma; Stem cell; Stromal cell; Leiomyosarcoma; Cellular differentiation; Pathology; Immunology; Cell biology; Medicine; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000413836,0.0001436757,0.000287783,0.00006316369,0.00008108174,0.000008018197,0.0001018891,0.00004902964,0.0001081308],"category_scores_gemma":[0.00001488371,0.00007419544,0.00008864997,0.0001727658,0.00006492768,0.00003214454,0.00007106534,0.00007146013,0.00001157499],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001367096,"about_ca_system_score_gemma":0.00009089504,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001191152,"about_ca_topic_score_gemma":0.0001758724,"domain_scores_codex":[0.998649,0.00008715731,0.0004486073,0.000135481,0.000395739,0.0002839846],"domain_scores_gemma":[0.9990726,0.0002334141,0.0002179986,0.0003354723,0.0000718339,0.00006873236],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002534724,0.002641655,0.5537848,0.0001241843,0.0002099082,0.00001031095,0.002701577,0.00001728149,0.381561,0.0005882094,0.000341836,0.0577658],"study_design_scores_gemma":[0.0009954665,0.0001240504,0.3028738,0.00006563662,0.00007482439,0.000004388992,0.0007661284,0.00002981282,0.6892218,0.000005606845,0.00576475,0.00007366257],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9919459,0.006520465,0.00001517232,0.0002693929,0.0002107191,0.0004649468,0.00001842316,0.000008360448,0.0005466307],"genre_scores_gemma":[0.9985538,0.0002699022,0.0002586222,0.00004226143,0.00004859522,0.00005403722,0.00000654829,0.00001560629,0.0007506441],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3076608,"threshold_uncertainty_score":0.3025602,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0250561660746687,"score_gpt":0.262617545241361,"score_spread":0.2375613791666923,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}