{"id":"W2038289519","doi":"10.1006/mthe.2001.0482","title":"Forced Myofiber Regeneration Promotes Dystrophin Gene Transfer and Improved Muscle Function Despite Advanced Disease in Old Dystrophic Mice","year":2001,"lang":"en","type":"article","venue":"Molecular Therapy","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Neurological Institute and Hospital; McGill University; Christie (Canada); McGill University Health Centre","funders":"","keywords":"Dystrophin; Duchenne muscular dystrophy; Myocyte; Biology; Regeneration (biology); mdx mouse; Muscular dystrophy; Cell biology; Genetic enhancement; Population; Gene; Medicine; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004055044,0.0005105946,0.0004101959,0.0005113729,0.0001102227,0.0003195248,0.0002894422,0.0003887144,0.0006134789],"category_scores_gemma":[0.0001821483,0.0002268361,0.0002999302,0.0001090006,0.0003338194,0.000312248,0.0003080763,0.0006781856,0.0002456314],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001750577,"about_ca_system_score_gemma":0.0001349579,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000252883,"about_ca_topic_score_gemma":0.0003972881,"domain_scores_codex":[0.9997752,0.00003526029,0.0000325263,0.00005998578,0.00004654505,0.00005043392],"domain_scores_gemma":[0.999631,0.00004476505,0.0001319894,0.00004026029,0.00002084752,0.0001310595],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001722721,0.00008126508,0.0002158939,0.00002041353,0.00000428848,0.00005535743,0.00002344813,0.00004606152,0.9981831,0.00008720715,0.00001694209,0.001093724],"study_design_scores_gemma":[0.00008531027,0.003496294,0.01046554,0.00002210752,0.00005479439,0.0005670917,0.00003532913,0.001483599,0.9806343,0.00011666,0.003025445,0.0000134326],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9953547,0.001048704,0.002835259,0.00004247923,0.00002107912,0.00003028921,0.0001491707,0.00009199925,0.0004263414],"genre_scores_gemma":[0.9877224,0.001198061,0.005505629,0.00006401489,0.00003767888,0.00007614656,0.0004780047,0.00007506093,0.004842984],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006134789,"threshold_uncertainty_score":0.002144516,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00536977934555163,"score_gpt":0.2099590570864096,"score_spread":0.2045892777408579,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}