{"id":"W2038315817","doi":"10.1007/s00018-014-1569-4","title":"Molecular functions and cellular roles of the ChlR1 (DDX11) helicase defective in the rare cohesinopathy Warsaw breakage syndrome","year":2014,"lang":"en","type":"review","venue":"Cellular and Molecular Life Sciences","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":60,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Saskatchewan","funders":"Natural Sciences and Engineering Research Council of Canada; National Institutes of Health","keywords":"Biology; Establishment of sister chromatid cohesion; Genetics; Bloom syndrome; Werner syndrome; Helicase; Gene; Chromatid; Chromosome","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004510276,0.0007931877,0.001298616,0.00176392,0.0001705053,0.0008237911,0.0009381027,0.0008892014,0.001296966],"category_scores_gemma":[0.0005450937,0.0002509211,0.0002992926,0.001555215,0.000496982,0.0007779414,0.0006428552,0.001269152,0.0009309851],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006134494,"about_ca_system_score_gemma":0.0007867354,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009740262,"about_ca_topic_score_gemma":0.001674331,"domain_scores_codex":[0.9998565,0.00001607887,0.00002576827,0.00002783675,0.00005945958,0.00001440007],"domain_scores_gemma":[0.9997732,0.00009110462,0.00004767242,0.000007164286,0.0000551117,0.00002577519],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001220541,0.00003976881,0.0003482883,0.01319199,0.0001273995,0.0005377285,0.00004996924,0.0004598258,0.005938592,0.002869589,0.02099024,0.9553244],"study_design_scores_gemma":[0.00004082376,0.00008331153,0.002032597,0.002241918,0.000282619,0.003806208,0.00007077067,0.0001555859,0.002381165,0.001965941,0.9869037,0.00003532894],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001593918,0.999216,0.0001134552,0.0001278499,0.00007185114,0.000001673277,0.00001218208,0.000004335183,0.0002932892],"genre_scores_gemma":[0.0009128519,0.9983828,0.0001481307,0.0000957719,0.0001028038,0.000002804151,0.00002783934,8.785884e-7,0.0003261247],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00176392,"threshold_uncertainty_score":0.004450917,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0124980802770337,"score_gpt":0.2470258689542514,"score_spread":0.2345277886772177,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}