{"id":"W2038469571","doi":"10.1021/bi500183c","title":"Structural Insight into How <i>Streptomyces coelicolor</i> Maltosyl Transferase GlgE Binds α-Maltose 1-Phosphate and Forms a Maltosyl-enzyme Intermediate","year":2014,"lang":"en","type":"article","venue":"Biochemistry","topic":"Enzyme Production and Characterization","field":"Biochemistry, Genetics and Molecular Biology","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Biotechnology and Biological Sciences Research Council; European Commission","keywords":"Streptomyces coelicolor; Enzyme; Chemistry; Transferase; Maltose; Biochemistry; Streptomyces; Stereochemistry; Biology; Mutant; Genetics; Bacteria","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005816095,0.0004006823,0.0001772543,0.00009800917,0.000196311,0.0003262193,0.000260602,0.0003944301,0.001279612],"category_scores_gemma":[0.00008278227,0.0001177408,0.0002666177,0.0001557235,0.0001901651,0.0002947407,0.000110667,0.0005123717,0.0004047311],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006870315,"about_ca_system_score_gemma":0.0003883898,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00477673,"about_ca_topic_score_gemma":0.004155326,"domain_scores_codex":[0.9999608,0.000005261214,0.000002091274,0.000009274775,0.0000106863,0.00001181939],"domain_scores_gemma":[0.9999611,0.000005122009,0.00001190978,0.00000365124,0.000003637144,0.00001443625],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005393495,0.00009909427,0.002963491,0.0001923104,0.00002955593,0.0008549359,0.0001384593,0.003177668,0.9840343,0.001645055,0.000791949,0.005533899],"study_design_scores_gemma":[0.000122375,0.0006087697,0.03191148,0.00006080046,0.0001337597,0.002115385,0.000508879,0.03123032,0.8951234,0.0008731607,0.03724455,0.00006708755],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9871601,0.001702935,0.004720194,0.0006223117,0.00004378637,0.00001911894,0.0006246074,0.0004248383,0.004682119],"genre_scores_gemma":[0.9903963,0.001469669,0.004710312,0.0001268863,0.00000918976,0.000006455742,0.0008974398,0.00003394262,0.002349816],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00477673,"threshold_uncertainty_score":0.009497821,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004929496142502449,"score_gpt":0.2109830541261304,"score_spread":0.2060535579836279,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}