{"id":"W2038479528","doi":"10.1073/pnas.1108862109","title":"Critical role of a transmembrane lysine in aminophospholipid transport by mammalian photoreceptor P <sub>4</sub> -ATPase ATP8A2","year":2012,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":101,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"National Eye Institute; Canadian Institutes of Health Research; Lundbeckfonden","keywords":"Transmembrane protein; Lysine; Transmembrane domain; ATPase; Chemistry; Ion transporter; Cell biology; Biophysics; Biology; Biochemistry; Membrane; Enzyme; Receptor; Amino acid","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001394415,0.000208238,0.000192976,0.00009703617,0.0002348725,0.0002723641,0.0001968124,0.0004139202,0.0005215873],"category_scores_gemma":[0.0002179381,0.0001276064,0.0001876623,0.00007359794,0.0002330289,0.0004231207,0.0002726748,0.0002312702,0.0003416706],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000332825,"about_ca_system_score_gemma":0.0002029403,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000312078,"about_ca_topic_score_gemma":0.0002656894,"domain_scores_codex":[0.9999297,0.00001441936,0.000007717905,0.00001861633,0.00001747623,0.00001203465],"domain_scores_gemma":[0.9998776,0.00001939412,0.00003772643,0.00000976007,0.00001839764,0.00003707836],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004990569,0.00001257028,0.001088604,0.00005198671,0.00000496458,0.0004011801,0.00003343247,0.0001120563,0.9956993,0.000442646,0.0000286353,0.001625656],"study_design_scores_gemma":[0.00005850511,0.0003251166,0.02086245,0.00001312253,0.00002581956,0.001525715,0.0001010124,0.002750359,0.9704917,0.0006166534,0.003215002,0.00001449055],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9959458,0.0009267987,0.001900124,0.00008210037,0.00001736613,0.000009404505,0.00005146439,0.00003066226,0.001036346],"genre_scores_gemma":[0.9978666,0.0002925375,0.001261945,0.00003251369,0.000006305019,0.000006343523,0.0000722944,0.000006092378,0.0004554368],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005215873,"threshold_uncertainty_score":0.002414882,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0145740189381905,"score_gpt":0.2653110094470692,"score_spread":0.2507369905088787,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}