{"id":"W2038505563","doi":"10.1371/journal.pbio.1001336","title":"p180 Promotes the Ribosome-Independent Localization of a Subset of mRNA to the Endoplasmic Reticulum","year":2012,"lang":"en","type":"article","venue":"PLoS Biology","topic":"RNA and protein synthesis mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":132,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Endoplasmic reticulum; Biology; Polysome; Calreticulin; Ribosome; Cell biology; Messenger RNA; Translation (biology); Translocon; Signal peptide; Secretory protein; Secretory pathway; ER retention; Membrane protein; Molecular biology; RNA; Gene; Biochemistry; Peptide sequence; Golgi apparatus; Membrane","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003948428,0.0001083324,0.0001569705,0.00002641362,0.00006661721,0.000003567553,0.0003106623,0.0001458714,0.00004407313],"category_scores_gemma":[0.0002090538,0.00005940125,0.0000679175,0.0000852558,0.0001082614,0.00000214992,0.0001041741,0.00005299643,0.00001319865],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000004386167,"about_ca_system_score_gemma":0.00002214554,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002785514,"about_ca_topic_score_gemma":0.00002782367,"domain_scores_codex":[0.9990422,0.0002424016,0.0002357869,0.0001638964,0.00009039275,0.0002253659],"domain_scores_gemma":[0.9992779,0.00003991598,0.000147946,0.0004078636,0.00008170043,0.00004470683],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003520453,0.00008393524,0.007697321,0.00001679081,0.00006070176,9.194721e-8,0.0001555345,0.000008724995,0.9898281,0.001504658,0.0001929903,0.0004159668],"study_design_scores_gemma":[0.0001176871,0.0003374777,0.0006245719,0.00001253998,0.00002982736,0.000007245083,0.00006834308,0.00001584823,0.9900699,0.0004160232,0.008225692,0.00007489962],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9935994,0.0006320656,0.003826552,0.0007032814,0.0001459435,0.0004904575,0.00004354078,0.000005547196,0.0005532534],"genre_scores_gemma":[0.9992133,0.0000627428,0.0001798136,0.0001790416,0.0001670882,0.00006605493,0.0000452559,0.00001210445,0.00007456804],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008032702,"threshold_uncertainty_score":0.2422313,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01504695637468312,"score_gpt":0.2399927250249768,"score_spread":0.2249457686502937,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}