{"id":"W2038518325","doi":"10.1002/eji.200838251","title":"The zinc finger protein Gfi1 is implicated in the regulation of IgG2b production and the expression of Iγ2b germline transcripts","year":2008,"lang":"en","type":"article","venue":"European Journal of Immunology","topic":"Blood disorders and treatments","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Montreal Clinical Research Institute","funders":"Deutsche Forschungsgemeinschaft","keywords":"Biology; Isotype; Germline; Germinal center; CD19; Antigen; Antibody; Immunoglobulin class switching; Secretion; Molecular biology; Transcription (linguistics); Messenger RNA; Stimulation; Lipopolysaccharide; Cell biology; B cell; Immunology; Gene; Monoclonal antibody; Endocrinology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005768831,0.00007087486,0.0001210098,0.00002660874,0.0000864037,0.000004088801,0.0001775772,0.00002959317,0.000002326772],"category_scores_gemma":[0.00008748924,0.00003241943,0.00006281271,0.00006478196,0.0003197578,0.000005434145,0.00002808343,0.0001046401,3.542391e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000002425327,"about_ca_system_score_gemma":0.00002050654,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006670666,"about_ca_topic_score_gemma":0.00000330185,"domain_scores_codex":[0.9988669,0.0005462252,0.0003417394,0.0000877495,0.00007524229,0.00008210407],"domain_scores_gemma":[0.9993188,0.00001667583,0.0003394266,0.0002175309,0.00009970176,0.000007901838],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008717146,0.0001086416,0.0005240246,0.000004909962,0.00006857554,0.000003330955,0.0009166949,0.000006611183,0.9925039,0.00003700068,0.0003153855,0.004639163],"study_design_scores_gemma":[0.00317194,0.0008334842,0.1013658,0.00006024181,0.00003862171,0.0003771399,0.0003178036,0.000003448603,0.890112,0.0001755488,0.003482369,0.00006167332],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9908683,0.006705522,0.00006616389,0.001952359,0.00004947027,0.0001847544,0.000001598412,8.152642e-7,0.0001709794],"genre_scores_gemma":[0.9984108,0.001335844,0.00007853924,0.00004190856,0.00003938194,0.000002814275,0.00000300703,0.000007775588,0.00007995374],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.102392,"threshold_uncertainty_score":0.1322026,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01025149318324213,"score_gpt":0.2111947309951444,"score_spread":0.2009432378119023,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}