{"id":"W2038539023","doi":"10.1038/nchem.1391","title":"Tackling tunicamycin","year":2012,"lang":"en","type":"letter","venue":"Nature Chemistry","topic":"Microbial Natural Products and Biosynthesis","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Chemistry; Glycobiology; Tunicamycin; Biochemistry; Streptomyces; Glycal; Biosynthesis; Glycosylation; Stereochemistry; Enzyme; Glycan; Glycoprotein; Stereoselectivity; Bacteria; Gene; Catalysis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007702469,0.0006500382,0.0007078089,0.0003079635,0.001583224,0.002132724,0.0006275059,0.01570661,0.003633965],"category_scores_gemma":[0.005213012,0.0003270226,0.0005649991,0.0002291621,0.001306592,0.001815449,0.00137051,0.01479038,0.002255868],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002506239,"about_ca_system_score_gemma":0.001033017,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001351032,"about_ca_topic_score_gemma":0.003496726,"domain_scores_codex":[0.9994763,0.00009194249,0.00005559952,0.00007353794,0.000182594,0.0001200006],"domain_scores_gemma":[0.9993095,0.0003419517,0.00008642975,0.00003451189,0.0000867878,0.0001407122],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003776881,0.00009759134,0.0005417669,0.000314625,0.00006285756,0.01032146,0.0001779223,0.0003197165,0.005093418,0.01194684,0.9052509,0.06549519],"study_design_scores_gemma":[0.0003381646,0.0002007401,0.000461636,0.0001541981,0.00004832613,0.004892062,0.0001585001,0.001027344,0.004462854,0.01538286,0.9728346,0.00003866757],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.004363468,0.0235683,0.0009208379,0.9096045,0.04986408,0.0000434797,0.0001024091,0.0001412672,0.01139156],"genre_scores_gemma":[0.07100137,0.02176316,0.002071681,0.7749963,0.0722088,0.0001941596,0.0001169384,0.00007572968,0.0575719],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.01570661,"threshold_uncertainty_score":0.01818413,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00916343046502053,"score_gpt":0.246089413538098,"score_spread":0.2369259830730775,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}