{"id":"W2038547684","doi":"10.1007/s12079-013-0216-4","title":"TGF‐β1 induces EMT reprogramming of porcine bladder urothelial cells into collagen producing fibroblasts‐like cells in a Smad2/Smad3‐dependent manner","year":2013,"lang":"en","type":"article","venue":"Journal of Cell Communication and Signaling","topic":"Connective Tissue Growth Factor Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":63,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"CTGF; Transforming growth factor; Epithelial–mesenchymal transition; Cancer research; Fibrosis; Downregulation and upregulation; Myofibroblast; SMAD; Fibroblast; Growth factor; Cell biology; Chemistry; Connective tissue; Biology; Cell culture; Pathology; Medicine; Receptor; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001675926,0.0001870181,0.0001909089,0.0001966313,0.0001420595,0.0002503598,0.00008945616,0.0001793779,0.001603043],"category_scores_gemma":[0.00008505085,0.000152,0.0004706481,0.000144701,0.000126221,0.0001226912,0.0001743766,0.0004322726,0.0003954242],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001088404,"about_ca_system_score_gemma":0.0002091587,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006175849,"about_ca_topic_score_gemma":0.0009189288,"domain_scores_codex":[0.9998544,0.00002471546,0.00002050266,0.00002518337,0.00003509236,0.00004008736],"domain_scores_gemma":[0.9999259,0.00001494865,0.0000202302,0.00001185858,0.00001010367,0.00001698022],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007822004,0.00003836694,0.0002250005,0.00006038217,0.000004559853,0.0001044519,0.00004244403,0.00007611331,0.9981292,0.00005152894,0.00006290937,0.00112698],"study_design_scores_gemma":[0.00002550737,0.0006709821,0.009955283,0.00002156468,0.0000206601,0.00058979,0.0001002815,0.001554906,0.9805459,0.00005472303,0.006450987,0.000009494819],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9891589,0.001887094,0.003883724,0.0001363781,0.00008653487,0.00007816595,0.0006566882,0.0000837097,0.004028721],"genre_scores_gemma":[0.9913484,0.001051325,0.003065666,0.0001217435,0.00001644409,0.00006150411,0.0008203723,0.00001909938,0.00349542],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001603043,"threshold_uncertainty_score":0.005362689,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01344099362996134,"score_gpt":0.2603869628515414,"score_spread":0.24694596922158,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}