{"id":"W2038630181","doi":"10.1067/mhj.2002.119770","title":"Choice of clinical outcomes in randomized trials of heart failure therapies: Disease-specific or overall outcomes?","year":2002,"lang":"en","type":"article","venue":"American Heart Journal","topic":"Heart Failure Treatment and Management","field":"Medicine","cited_by":37,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University; Hamilton Health Sciences","funders":"","keywords":"Medicine; Generalizability theory; Spurious relationship; Confounding; Outcome (game theory); Randomized controlled trial; Intensive care medicine; Clinical trial; MEDLINE; Disease; Internal medicine; Statistics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["metaresearch"],"consensus_categories":["metaresearch"],"category_scores_codex":[0.4223105,0.003820063,0.02671748,0.003846861,0.002236761,0.009059193,0.005275685,0.0118924,0.01120117],"category_scores_gemma":[0.5164688,0.003237546,0.0311781,0.004804257,0.009253331,0.01251568,0.006137775,0.01267473,0.001536898],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002831156,"about_ca_system_score_gemma":0.00344102,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006450837,"about_ca_topic_score_gemma":0.001422324,"domain_scores_codex":[0.3408332,0.5705261,0.05956167,0.0161544,0.01007818,0.002846426],"domain_scores_gemma":[0.3010193,0.6382311,0.03156356,0.01843092,0.005035378,0.005719743],"domain_codex":"methods","domain_gemma":"methods","domain_candidate":"methods","domain_consensus":"methods","study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.3681526,0.001020089,0.06554209,0.05183184,0.284473,0.0005851338,0.001757128,0.004511497,0.001532005,0.01820209,0.02153374,0.1808587],"study_design_scores_gemma":[0.4320521,0.0322903,0.08312195,0.01996721,0.2055755,0.001476278,0.001956549,0.02436357,0.004074007,0.1566886,0.03684341,0.00159059],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.2697361,0.4251302,0.1273688,0.1036679,0.03100895,0.0107576,0.01124275,0.001051959,0.0200358],"genre_scores_gemma":[0.9009923,0.0114814,0.04228029,0.02595503,0.007208676,0.006931029,0.003288388,0.0002661686,0.001596722],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.5776895,"threshold_uncertainty_score":0.7123941,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1663807945985347,"score_gpt":0.4233198366215077,"score_spread":0.256939042022973,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}