{"id":"W2038642995","doi":"10.1002/eji.200737902","title":"Interleukin‐10‐induced MARCH1 mediates intracellular sequestration of MHC class II in monocytes","year":2008,"lang":"en","type":"article","venue":"European Journal of Immunology","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":161,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute for Research in Immunology and Cancer; Université de Sherbrooke; Université de Montréal","funders":"National Center for Research Resources; National Institute of Allergy and Infectious Diseases; Natural Sciences and Engineering Research Council of Canada; Canadian Liver Foundation; Canadian Institutes of Health Research; Institut National de la Santé et de la Recherche Médicale; National Cancer Institute; National Institutes of Health","keywords":"MHC class II; Biology; Antigen presentation; MHC class I; Antigen processing; Ubiquitin ligase; Transfection; Molecular biology; Major histocompatibility complex; Cell biology; Ubiquitin; Antigen; Immune system; T cell; Immunology; Cell culture; Biochemistry; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001235876,0.0003006705,0.0002064065,0.0001290525,0.0001679747,0.0003430149,0.0001026822,0.0001935716,0.001570922],"category_scores_gemma":[0.0001335479,0.0001342843,0.0002119737,0.00009021301,0.0001342379,0.000145317,0.000209507,0.0004425329,0.0007566354],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003646801,"about_ca_system_score_gemma":0.0001544311,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003292764,"about_ca_topic_score_gemma":0.000404715,"domain_scores_codex":[0.999853,0.00002540577,0.000009477694,0.00002169042,0.000029802,0.0000605003],"domain_scores_gemma":[0.9998939,0.00001598442,0.00003555425,0.00001249672,0.00001424951,0.00002776838],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001159119,0.000009061574,0.0003073809,0.00003036737,0.000002796691,0.0000512541,0.0000109271,0.00002619719,0.9986693,0.00005135994,0.00004539558,0.0006801449],"study_design_scores_gemma":[0.00003388782,0.000168607,0.01282091,0.000008520821,0.00001598584,0.0004011998,0.00004281869,0.0009732162,0.9831967,0.00005427915,0.002279056,0.000004865479],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9962291,0.001440618,0.001249667,0.0001212758,0.00002131342,0.00001087817,0.0002012336,0.00003267062,0.0006933471],"genre_scores_gemma":[0.9961509,0.0005719422,0.000879817,0.00005056871,0.00001329117,0.00001660498,0.0003850814,0.000008504758,0.001923284],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001570922,"threshold_uncertainty_score":0.005255222,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02406831464142862,"score_gpt":0.2332397851355068,"score_spread":0.2091714704940782,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}