{"id":"W2038672919","doi":"10.1073/pnas.0130233100","title":"Wnt-5A augments repopulating capacity and primitive hematopoietic development of human blood stem cells <i>in</i> <i>vivo</i>","year":2003,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Wnt/β-catenin signaling in development and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":212,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"","keywords":"Wnt signaling pathway; Haematopoiesis; Stem cell; Biology; Progenitor cell; Hematopoietic stem cell; Cell biology; Stromal cell; Immunology; In vivo; Cancer research; Signal transduction; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009924395,0.00009146689,0.000137778,0.00005801222,0.0001269287,0.00000869775,0.0002549785,0.00007750718,0.000003938703],"category_scores_gemma":[0.00006097218,0.00007011318,0.0000337702,0.0002175548,0.0003537258,0.00001653436,0.00009390301,0.00006652946,7.298026e-8],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001403027,"about_ca_system_score_gemma":0.00005488461,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002098128,"about_ca_topic_score_gemma":2.131761e-7,"domain_scores_codex":[0.9987342,0.00000870276,0.0004022663,0.0002383376,0.0004869992,0.000129486],"domain_scores_gemma":[0.9993881,0.00001550555,0.0004146692,0.000008447535,0.0001498756,0.00002341398],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000004263167,0.00003649936,0.02572912,0.00007600195,0.0000173552,4.213315e-9,0.0003418595,0.00001164936,0.9717581,0.001938462,0.00004835753,0.00003827496],"study_design_scores_gemma":[0.0002274656,0.00003033649,0.0060289,0.0001293595,0.000008183979,0.00000389091,0.0002378457,0.000003740238,0.9914379,0.001732356,0.0000776728,0.00008230864],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970593,0.0001518697,0.000001146892,0.00003439948,0.00001331725,0.0001261881,0.000003294569,0.000001865224,0.002608641],"genre_scores_gemma":[0.9966848,0.00001681533,0.003055343,0.00005411601,0.00001211166,0.000009978269,1.29279e-7,0.000003793114,0.000162842],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01970022,"threshold_uncertainty_score":0.2859132,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03882877679425854,"score_gpt":0.2760529371520908,"score_spread":0.2372241603578323,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}