{"id":"W2038675022","doi":"10.1016/j.biolcel.2004.05.003","title":"Internal organisation of the nucleus: assembly of compartments by macromolecular crowding and the nuclear matrix model","year":2004,"lang":"en","type":"review","venue":"Biology of the Cell","topic":"Nuclear Structure and Function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":90,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval; Hôtel-Dieu de Québec; Hotel Dieu Hospital","funders":"Canadian Institutes of Health Research","keywords":"Macromolecular crowding; Macromolecule; Nucleus; Compartment (ship); Nucleolus; Biophysics; Biology; Macromolecular Substances; Cell nucleus; Matrix (chemical analysis); Nuclear matrix; Cellular compartment; Fibril; Cell biology; Chemistry; DNA; Biochemistry; Cell; Chromatin","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007273122,0.001114424,0.001824464,0.002167549,0.0005159284,0.001156006,0.001913042,0.002031005,0.001494482],"category_scores_gemma":[0.0005822714,0.0004064177,0.0003883553,0.002038225,0.002058196,0.002918725,0.0007926486,0.001605565,0.002016361],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00197269,"about_ca_system_score_gemma":0.001092508,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002155589,"about_ca_topic_score_gemma":0.001691279,"domain_scores_codex":[0.9997943,0.00003285655,0.00002236026,0.00005076799,0.00007966645,0.00002010629],"domain_scores_gemma":[0.9997037,0.0001162134,0.00004538539,0.00001588563,0.00008461901,0.00003410967],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000100323,0.0000627642,0.0003012985,0.0136877,0.00007049659,0.0005766341,0.0001925477,0.00389354,0.005370053,0.05839033,0.02552892,0.8918254],"study_design_scores_gemma":[0.00001351185,0.00005734611,0.0004768069,0.001474401,0.00004775917,0.001780706,0.0001025731,0.0006103865,0.001682877,0.01905681,0.9746609,0.00003587991],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001934513,0.9964721,0.001187357,0.0003231055,0.0002444025,0.000005145083,0.000008853828,0.00001315548,0.001552397],"genre_scores_gemma":[0.001752453,0.9958621,0.0008031452,0.0001673133,0.0001999629,0.00001084963,0.0000210765,0.000002716584,0.001180431],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002167549,"threshold_uncertainty_score":0.01431292,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009243206122583194,"score_gpt":0.2582009419235684,"score_spread":0.2489577358009852,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}