{"id":"W2038700648","doi":"10.1007/s10495-014-0993-0","title":"Lymphocyte-derived microparticles induce apoptosis of airway epithelial cells through activation of p38 MAPK and production of arachidonic acid","year":2014,"lang":"en","type":"article","venue":"APOPTOSIS","topic":"Extracellular vesicles in disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal; Centre Hospitalier Universitaire Sainte-Justine","funders":"Canadian Institutes of Health Research","keywords":"Cell biology; Apoptosis; Oxidative stress; Respiratory epithelium; Programmed cell death; p38 mitogen-activated protein kinases; Arachidonic acid; Biology; Reactive oxygen species; MAPK/ERK pathway; Chemistry; Epithelium; Signal transduction; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000206875,0.0001576926,0.0002451491,0.00004602657,0.00004112041,0.00000586861,0.0001576069,0.0001395471,0.00000905763],"category_scores_gemma":[0.0001767148,0.0001582548,0.0001004548,0.0001279,0.0002504171,0.00001717376,0.0001043673,0.00005170918,0.000001962464],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001525903,"about_ca_system_score_gemma":0.00005377032,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006165286,"about_ca_topic_score_gemma":0.000002458299,"domain_scores_codex":[0.998816,0.0001255735,0.0003889836,0.0003411356,0.0001568209,0.0001715021],"domain_scores_gemma":[0.9989642,0.0000237798,0.0003595369,0.0004566389,0.0001461458,0.00004972208],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002236964,0.0002032494,0.0006065505,0.0001662541,0.0000706741,1.984757e-8,0.0002253169,0.00005864861,0.9918472,0.0000755416,0.00007956097,0.006443352],"study_design_scores_gemma":[0.0006069815,0.0002673369,0.0009028706,0.00004395961,0.00007478211,8.589242e-7,0.0001430353,0.0000291433,0.9974051,0.0001851731,0.000193718,0.0001470556],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977025,0.0003285049,0.001420963,0.00009820332,0.0001261538,0.0002123098,0.00002068782,0.000008182622,0.00008247752],"genre_scores_gemma":[0.9963237,0.0003087875,0.003131681,0.00003298672,0.00009904715,0.00001481582,0.00003110517,0.00002475454,0.00003308912],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006296297,"threshold_uncertainty_score":0.6453443,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008516469424995166,"score_gpt":0.2247693970032115,"score_spread":0.2162529275782163,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}