{"id":"W2038733266","doi":"10.1038/ncb2520","title":"Diverse epigenetic strategies interact to control epidermal differentiation","year":2012,"lang":"en","type":"article","venue":"Nature Cell Biology","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":153,"is_retracted":false,"has_abstract":false,"ca_institutions":"BC Centre for Disease Control","funders":"Cancer Research UK; Wellcome Trust","keywords":"Epigenetics; Biology; Chromatin; Cellular differentiation; Stem cell; Cell biology; Gene regulatory network; Regulation of gene expression; Gene expression; Computational biology; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002820034,0.0003009424,0.000258914,0.0003487854,0.0003080569,0.001298849,0.0005266793,0.0004266717,0.00169426],"category_scores_gemma":[0.0003435806,0.0003331914,0.0002878244,0.0002428781,0.000518324,0.001050654,0.001009876,0.000868357,0.0007143466],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004108766,"about_ca_system_score_gemma":0.0002117605,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002141906,"about_ca_topic_score_gemma":0.000675442,"domain_scores_codex":[0.9997754,0.00001903996,0.0000136702,0.00005707673,0.00008390368,0.00005098488],"domain_scores_gemma":[0.9997976,0.00003402678,0.00004277787,0.00004213117,0.00004195868,0.00004145616],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005710892,0.00001127891,0.001024919,0.00003664803,0.00001095388,0.00009537549,0.00004684981,0.000249397,0.9846641,0.004351082,0.0001333785,0.009318852],"study_design_scores_gemma":[0.00002019615,0.00008517304,0.02393006,0.00002724304,0.00004492915,0.0003930905,0.0002430597,0.003966989,0.9556102,0.004348376,0.01130446,0.00002627085],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9025444,0.009774683,0.06181147,0.001129385,0.0002988603,0.00005902158,0.0003942657,0.0006880212,0.02329987],"genre_scores_gemma":[0.9857246,0.001984377,0.004773812,0.0002789288,0.00003722283,0.00001881457,0.0001957298,0.0001094167,0.006877113],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00169426,"threshold_uncertainty_score":0.005667865,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004057445860218122,"score_gpt":0.2398661572959095,"score_spread":0.2358087114356914,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}