{"id":"W2038744986","doi":"10.1002/mc.20126","title":"DNA methylation in the CTCF‐binding site I and the expression pattern of the <i>H19</i> gene: Does positive expression predict poor prognosis in early stage head and neck carcinomas?","year":2005,"lang":"en","type":"article","venue":"Molecular Carcinogenesis","topic":"Genetic Syndromes and Imprinting","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto; Ontario Institute for Cancer Research","funders":"Fundação para o Desenvolvimento da UNESP; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior; Division of Materials Research; Fundação de Amparo à Pesquisa do Estado de São Paulo","keywords":"CTCF; Biology; Methylation; Gene silencing; DNA methylation; Genomic imprinting; Imprinting (psychology); Cancer research; Gene; Molecular biology; Chromatin; Gene expression; Genetics; Enhancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003511126,0.0001929606,0.0002588069,0.0007155389,0.0001664851,0.0002798305,0.0002358361,0.0003805945,0.0008599471],"category_scores_gemma":[0.001115442,0.0001618397,0.0001684318,0.0004391808,0.0003144389,0.0001827626,0.0001457598,0.0002649775,0.0002558954],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002096347,"about_ca_system_score_gemma":0.0001568597,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00357208,"about_ca_topic_score_gemma":0.003350521,"domain_scores_codex":[0.9998653,0.0000334547,0.00001225933,0.00002803224,0.00002918976,0.00003177526],"domain_scores_gemma":[0.9994761,0.0001771288,0.000163766,0.00003434781,0.00005437561,0.00009436398],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0004476867,0.00002389814,0.9878168,0.0000146239,0.00004853088,0.000130818,0.00007079542,0.00004375916,0.00790314,0.000008668666,0.00005343619,0.003437849],"study_design_scores_gemma":[0.000007232448,0.0001082214,0.9979481,0.00000261846,0.00003131334,0.0004943283,0.00006296566,0.0003290687,0.0008786001,0.0000183298,0.0001159706,0.000003285375],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9994128,0.0003087899,0.00007017744,0.00002055263,0.000002269146,0.000002790777,0.00004561976,0.000001905284,0.0001350486],"genre_scores_gemma":[0.9997061,0.00008102028,0.00004148076,0.000005862287,0.000007398621,0.000002033878,0.0000671915,9.318549e-7,0.00008795037],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00357208,"threshold_uncertainty_score":0.007102549,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00651171642146533,"score_gpt":0.2160510322379391,"score_spread":0.2095393158164738,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}