{"id":"W2038744986","doi":"10.1002/mc.20126","title":"DNA methylation in the CTCF‐binding site I and the expression pattern of the <i>H19</i> gene: Does positive expression predict poor prognosis in early stage head and neck carcinomas?","year":2005,"lang":"en","type":"article","venue":"Molecular Carcinogenesis","topic":"Genetic Syndromes and Imprinting","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto; Ontario Institute for Cancer Research","funders":"Fundação para o Desenvolvimento da UNESP; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior; Division of Materials Research; Fundação de Amparo à Pesquisa do Estado de São Paulo","keywords":"CTCF; Biology; Methylation; Gene silencing; DNA methylation; Genomic imprinting; Imprinting (psychology); Cancer research; Gene; Molecular biology; Chromatin; Gene expression; Genetics; Enhancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005975946,0.0002169598,0.0002214701,0.00006768886,0.0001450234,0.00004798743,0.0002580155,0.0001420349,0.000001803805],"category_scores_gemma":[0.00006421926,0.0001131533,0.0001102143,0.0001703336,0.0001457892,0.00001253327,0.0003255243,0.0001418803,3.863267e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001545158,"about_ca_system_score_gemma":0.00002710883,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003672151,"about_ca_topic_score_gemma":0.0001789559,"domain_scores_codex":[0.998068,0.0006047453,0.000348959,0.0004323419,0.0002678186,0.0002781614],"domain_scores_gemma":[0.9993157,0.00005435042,0.0001695584,0.0003697028,0.00004690914,0.00004382446],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002918368,0.00002434415,0.3209528,0.00001866175,0.00001043683,0.000002378182,0.001022164,0.00005142845,0.6758496,0.000001292317,0.000002874786,0.002034861],"study_design_scores_gemma":[0.0008267824,0.00005419091,0.4304654,0.00006110856,0.00002266774,0.000009950713,0.0002578644,0.000131916,0.5680361,0.000003712208,0.00004154217,0.000088709],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9959217,0.00248402,0.0002818333,0.0004389094,0.0000398896,0.0007521472,0.00004126997,0.000003215565,0.00003698087],"genre_scores_gemma":[0.9990187,0.0001960604,0.0003892661,0.0001944131,0.0000467284,0.00008443169,0.00002263471,0.00002519389,0.00002253333],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1095126,"threshold_uncertainty_score":0.4614257,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00651171642146533,"score_gpt":0.2160510322379391,"score_spread":0.2095393158164738,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}