{"id":"W2038758551","doi":"10.1111/j.1440-1681.2009.05193.x","title":"p38 MITOGEN‐ACTIVATED PROTEIN KINASE (MAPK) IS ACTIVATED BY NORADRENALINE AND SERVES A CARDIOPROTECTIVE ROLE, WHEREAS ADRENALINE INDUCES p38 MAPK DEPHOSPHORYLATION","year":2009,"lang":"en","type":"article","venue":"Clinical and Experimental Pharmacology and Physiology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Dephosphorylation; MAPK/ERK pathway; p38 mitogen-activated protein kinases; Protein kinase A; Kinase; Programmed cell death; Mitogen-activated protein kinase; Apoptosis; Chemistry; Cell biology; Phosphorylation; Fragmentation (computing); Molecular biology; Biology; Biochemistry; Phosphatase","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001846725,0.0009387057,0.0003903865,0.000240863,0.0003034388,0.0002693245,0.0002327911,0.000335189,0.002272241],"category_scores_gemma":[0.0001694566,0.0001813773,0.0004362813,0.0001447134,0.0002505527,0.000406689,0.0002786288,0.0005452226,0.000654662],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002251734,"about_ca_system_score_gemma":0.0002517361,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000176182,"about_ca_topic_score_gemma":0.0004074424,"domain_scores_codex":[0.9998757,0.00001373267,0.00001128407,0.00003671579,0.00003022585,0.00003221823],"domain_scores_gemma":[0.9998604,0.00002070343,0.00005505478,0.00001208,0.00002018291,0.00003153382],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001980179,0.0000477203,0.0003805841,0.0002093639,0.00001229687,0.0001710658,0.00002418912,0.00002940798,0.9948158,0.00008412325,0.00008832561,0.003939012],"study_design_scores_gemma":[0.00006212841,0.001502881,0.03733821,0.00005238307,0.00008985773,0.00208145,0.0001270218,0.0007869463,0.9484898,0.0003984072,0.009055062,0.00001585578],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9324268,0.04795742,0.01125905,0.0005860769,0.0003927936,0.0001191488,0.00108162,0.0002997037,0.005877483],"genre_scores_gemma":[0.9699503,0.02034896,0.004113213,0.0001590399,0.0001865286,0.0001315747,0.0007297932,0.00003039117,0.004350231],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002272241,"threshold_uncertainty_score":0.00760144,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01238781286727789,"score_gpt":0.3063453918247989,"score_spread":0.293957578957521,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}