{"id":"W2038758551","doi":"10.1111/j.1440-1681.2009.05193.x","title":"p38 MITOGEN‐ACTIVATED PROTEIN KINASE (MAPK) IS ACTIVATED BY NORADRENALINE AND SERVES A CARDIOPROTECTIVE ROLE, WHEREAS ADRENALINE INDUCES p38 MAPK DEPHOSPHORYLATION","year":2009,"lang":"en","type":"article","venue":"Clinical and Experimental Pharmacology and Physiology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Dephosphorylation; MAPK/ERK pathway; p38 mitogen-activated protein kinases; Protein kinase A; Kinase; Programmed cell death; Mitogen-activated protein kinase; Apoptosis; Chemistry; Cell biology; Phosphorylation; Fragmentation (computing); Molecular biology; Biology; Biochemistry; Phosphatase","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002079773,0.0003296422,0.0004837418,0.00003647028,0.0002288963,0.0000221644,0.000104135,0.0005014688,0.0001610633],"category_scores_gemma":[0.00002247008,0.0002850947,0.0001022927,0.0000793577,0.0003580806,0.00002367954,0.0001301251,0.0003296819,0.000002462854],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000009242027,"about_ca_system_score_gemma":0.00002914124,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008045988,"about_ca_topic_score_gemma":0.000001798263,"domain_scores_codex":[0.9980621,0.0003368259,0.0004241847,0.0007725832,0.00007560966,0.0003287254],"domain_scores_gemma":[0.9993616,0.000041531,0.0001765781,0.000131423,0.00006029954,0.0002285479],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002420349,0.000308614,0.0001073892,0.00001405766,0.000239166,0.000003828318,0.0001555671,0.000003586047,0.99203,0.0000203422,0.0007872881,0.003909859],"study_design_scores_gemma":[0.002833205,0.002215008,0.001515698,0.0000183135,0.00005254438,0.00001871729,0.0001874773,0.00009287928,0.9899644,0.0005545203,0.002215405,0.0003318879],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9894167,0.009418153,0.00004153701,0.0002849331,0.0002183794,0.0005127425,0.00005202008,0.00002387702,0.00003171144],"genre_scores_gemma":[0.9970352,0.0005650115,0.0001299765,0.001448031,0.0004010735,0.00007025628,0.0001935133,0.00001992311,0.0001370002],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008853142,"threshold_uncertainty_score":0.9999601,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01238781286727789,"score_gpt":0.3063453918247989,"score_spread":0.293957578957521,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}