{"id":"W2038771520","doi":"10.1016/j.celrep.2015.03.056","title":"Central Role of ULK1 in Type I Interferon Signaling","year":2015,"lang":"en","type":"article","venue":"Cell Reports","topic":"Myeloproliferative Neoplasms: Diagnosis and Treatment","field":"Medicine","cited_by":75,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; University Health Network","funders":"National Cancer Institute; University of Illinois at Chicago; Northwestern University; U.S. Department of Veterans Affairs","keywords":"ULK1; Interferon; Biology; Protein kinase A; Cancer research; Transcription factor; Cell biology; Mediator; Regulator; MAPK/ERK pathway; p38 mitogen-activated protein kinases; Kinase; Signal transduction; Gene; Immunology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001610228,0.0003791713,0.0002173085,0.0001809649,0.0004629412,0.0006670287,0.0002627276,0.0002976277,0.001474082],"category_scores_gemma":[0.0001397791,0.0001031379,0.000225877,0.00009778652,0.0002679727,0.0004475718,0.0003967974,0.0005859598,0.000673409],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007912766,"about_ca_system_score_gemma":0.0002545005,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001682088,"about_ca_topic_score_gemma":0.0001491586,"domain_scores_codex":[0.9998844,0.00001707581,0.000009453861,0.00003519047,0.0000191189,0.00003481925],"domain_scores_gemma":[0.9999049,0.0000121914,0.00003467337,0.00001125523,0.00001022188,0.0000267528],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006099626,0.00005442537,0.001902497,0.0002313417,0.0000112223,0.0002912337,0.00007245164,0.0003792113,0.9831132,0.002011179,0.0003057446,0.01101747],"study_design_scores_gemma":[0.00002261383,0.000154894,0.008375099,0.00002394148,0.00001710999,0.0008486637,0.00007227909,0.001412766,0.9770507,0.0007046977,0.011307,0.00001030829],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9588664,0.02593275,0.007193133,0.0009635076,0.0001352128,0.00003682009,0.0004661428,0.0002246683,0.006181325],"genre_scores_gemma":[0.9937162,0.002794292,0.001734274,0.00007023838,0.00003036032,0.00001447467,0.0002346073,0.000009294576,0.001396325],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001474082,"threshold_uncertainty_score":0.005741179,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0241437392744405,"score_gpt":0.2676767219000215,"score_spread":0.243532982625581,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}