{"id":"W2038791554","doi":"10.1074/jbc.m105067200","title":"Endocytosis Is Enhanced in Tangier Fibroblasts","year":2001,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Lipid metabolism and biosynthesis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":63,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; University of Ottawa","funders":"Canadian Institutes of Health Research; University of Washington","keywords":"Tangier disease; Endocytosis; Cell biology; Chemistry; Biology; Biochemistry; Transporter; ABCA1; Cell","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001179094,0.0004251923,0.0004506344,0.0003964905,0.0002114722,0.0003136425,0.00009971005,0.0002995455,0.001434337],"category_scores_gemma":[0.0001487037,0.0001747202,0.0002275001,0.0001470845,0.0001781991,0.0001818429,0.0002095677,0.0003168233,0.000368472],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002393334,"about_ca_system_score_gemma":0.0000993837,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008538162,"about_ca_topic_score_gemma":0.0007048331,"domain_scores_codex":[0.9997938,0.00002363554,0.00002477225,0.00004613514,0.00008221505,0.00002939811],"domain_scores_gemma":[0.9998109,0.00004546187,0.00004764627,0.00002753019,0.00002170945,0.00004677562],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000850462,0.000008506554,0.0002317099,0.00001791563,0.000005610962,0.0003116713,0.00002042556,0.00001237253,0.9986843,0.00003118425,0.00001921348,0.0005720875],"study_design_scores_gemma":[0.00003603722,0.0003163025,0.02650384,0.000007451836,0.00004438965,0.004622268,0.00007923188,0.0005483524,0.9654092,0.0001245611,0.002292653,0.00001582703],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964588,0.001343313,0.0008653169,0.00005636637,0.00001973527,0.000009141319,0.0002331785,0.00008500092,0.0009290877],"genre_scores_gemma":[0.9957342,0.0007048986,0.0007251037,0.00005023106,0.00001384957,0.00001960013,0.0002441109,0.00002125619,0.002486804],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001434337,"threshold_uncertainty_score":0.004798293,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01451665176586521,"score_gpt":0.2454363919575527,"score_spread":0.2309197401916875,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}