{"id":"W2038845671","doi":"10.1002/art.10357","title":"Study of the role of leukotriene B<sub>4</sub> in abnormal function of human subchondral osteoarthritis osteoblasts: Effects of cyclooxygenase and/or 5‐lipoxygenase inhibition","year":2002,"lang":"en","type":"article","venue":"Arthritis & Rheumatism","topic":"Osteoarthritis Treatment and Mechanisms","field":"Medicine","cited_by":73,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Hôpital Notre-Dame","funders":"","keywords":"Osteocalcin; Cyclooxygenase; Chemistry; Osteoblast; Endocrinology; Internal medicine; Prostaglandin E2; Osteoarthritis; Eicosanoid; Alkaline phosphatase; Prostaglandin E; Medicine; In vitro; Enzyme; Biochemistry; Arachidonic acid; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002377786,0.0003226825,0.0009752596,0.0003660813,0.0001005897,0.000009068254,0.00009855237,0.0001760524,0.00006890664],"category_scores_gemma":[0.0001254243,0.0002712061,0.0001831478,0.0005633938,0.000258764,0.0003078758,0.0001136864,0.0002231293,0.000005099289],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004467991,"about_ca_system_score_gemma":0.00003994751,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003069427,"about_ca_topic_score_gemma":0.003148423,"domain_scores_codex":[0.9972026,0.0002305213,0.001238347,0.0003778944,0.0005980589,0.0003525836],"domain_scores_gemma":[0.9983885,0.0001552674,0.0006302925,0.0005180491,0.0001795078,0.0001284427],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004347365,0.002065157,0.0107083,0.0003589708,0.00005500529,0.00009921874,0.004153521,0.000004702482,0.7351736,0.0004891311,0.00002598961,0.2464317],"study_design_scores_gemma":[0.0262352,0.01994214,0.0514611,0.005651523,0.0001543671,0.0001828632,0.002459555,0.00001872299,0.893248,0.0004061573,0.000008925791,0.0002314674],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9893973,0.008061662,0.000002924981,0.00002163177,0.000202738,0.002018158,0.00005538363,0.00002929965,0.000210848],"genre_scores_gemma":[0.998123,0.001547408,0.00005696623,0.0000152001,0.00002615701,0.0001317973,0.00003050627,0.0000434445,0.00002548097],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2462002,"threshold_uncertainty_score":0.999974,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007288410374736091,"score_gpt":0.2063877687828623,"score_spread":0.1990993584081262,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}