{"id":"W2038934023","doi":"10.1126/science.1231321","title":"Developmental Decline in Neuronal Regeneration by the Progressive Change of Two Intrinsic Timers","year":2013,"lang":"en","type":"article","venue":"Science","topic":"Genetics, Aging, and Longevity in Model Organisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":156,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"National Institute of General Medical Sciences","keywords":"Axon; Regeneration (biology); Biology; Neuroscience; Caenorhabditis elegans; Microtubule; Cell biology; Mitosis; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001830596,0.0002333976,0.0002066115,0.0002257202,0.0001500001,0.0004301036,0.000263226,0.0002415122,0.0006870578],"category_scores_gemma":[0.0002194864,0.0001641679,0.0002287118,0.00008733885,0.0002649662,0.0003226594,0.0003085401,0.0006092844,0.0001862837],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003311808,"about_ca_system_score_gemma":0.0002528389,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002544908,"about_ca_topic_score_gemma":0.0003993138,"domain_scores_codex":[0.999864,0.00001093785,0.00001372623,0.00004224038,0.00004614045,0.00002303994],"domain_scores_gemma":[0.9998486,0.00002081002,0.00005043612,0.0000247127,0.00002201475,0.00003339957],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004877107,0.000008492553,0.0004214504,0.00001184718,0.000003806053,0.00003376869,0.00001229557,0.00004768529,0.9973525,0.0004259404,0.00001420015,0.001619252],"study_design_scores_gemma":[0.000008326923,0.0001300765,0.01216807,0.000004536544,0.00001825436,0.0002853136,0.0000230517,0.0009610727,0.9839256,0.0002110975,0.002256809,0.000007831079],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9922705,0.001445031,0.004577235,0.00005596375,0.00002383307,0.000006860115,0.0001032984,0.0001685792,0.001348883],"genre_scores_gemma":[0.9962287,0.000534818,0.001620457,0.00003272386,0.000006217622,0.00001601696,0.0001158373,0.00002500536,0.001420351],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006870578,"threshold_uncertainty_score":0.002402902,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0155366800346323,"score_gpt":0.2574374416147181,"score_spread":0.2419007615800858,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}